7-keto-DHEA is a supplement that is often marketed as a weight loss aid. It is a by-product of dehydroepiandrosterone (DHEA), a chemical produced by glands near the kidneys. Unlike DHEA, 7-keto-DHEA is not converted to hormones like androgen and estrogen. It is believed to promote weight loss by increasing the body's metabolism and converting more energy to heat instead of storing it as fat. However, there is limited scientific evidence supporting the effectiveness of 7-keto-DHEA for weight loss and improving lean body mass.
Characteristics | Values |
---|---|
Weight Loss | Developing research suggests that 7-keto-DHEA might significantly help obese women lose weight and fat. |
Lean Body Mass | 7-keto-DHEA is also used to improve lean body mass and build muscle. |
Thyroid Activity | It is used to increase the activity of the thyroid gland. |
Immune System | It is used to boost the immune system. |
Memory | It is used to enhance memory. |
Aging | It is used to slow aging. |
Metabolism | It is used to speed up the metabolism. |
What You'll Learn
Weight loss
7-keto-DHEA is a supplement that may increase your metabolism and lead to weight loss. It is a by-product of dehydroepiandrosterone (DHEA), a chemical produced by the adrenal glands located on top of each of the kidneys. Unlike DHEA, 7-keto-DHEA is not converted to steroid hormones such as androgen and estrogen. This means that when taken as an oral supplement, it does not increase the amount of these hormones in the blood.
There is some evidence to suggest that 7-keto-DHEA may be effective for weight loss when used alongside a reduced-calorie diet and exercise. In one eight-week study, participants who were overweight and took 200 mg per day of 7-Keto lost 6.3 pounds (2.88 kg), compared to a 2.1-pound (0.97 kg) weight loss in the placebo group. Another study found that those who took a supplement containing 7-keto-DHEA lost 4.8 pounds (2.2 kg), compared to 1.6 pounds (0.72 kg) in the placebo group. However, it is unclear whether this effect can be attributed solely to 7-Keto.
Furthermore, 7-Keto has been found to increase the resting metabolic rate (RMR) of people who are overweight. One study showed that 7-Keto increased metabolism by 1.4% above baseline levels, resulting in an extra 96 calories burned per day. This suggests that 7-Keto may aid weight loss by increasing the number of calories burned.
While 7-Keto is likely safe and has a low risk of serious side effects, there are some considerations to keep in mind. It has been banned by the World Anti-Doping Association (WADA) for use in sports, and it may influence hormones in men when applied to the skin as a gel. Additionally, it is important to consult a physician before taking this supplement, especially for those with a thyroid disorder or who are taking thyroid hormones.
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Lean body mass
Maintaining or increasing lean body mass is important for several reasons. Firstly, it helps improve your metabolic rate, as muscle tissue is more metabolically active than fat tissue. This means that the more lean body mass you have, the more calories you burn at rest. Additionally, having a higher percentage of lean body mass can improve your physical performance and overall health.
There are several ways to increase lean body mass. One method is through resistance training, such as weight lifting or bodyweight exercises. This type of training stimulates muscle protein synthesis, leading to increased muscle mass and strength. Another way to increase lean body mass is by consuming a sufficient amount of protein, which is essential for muscle growth and repair. Aim for a balanced diet that includes lean proteins, complex carbohydrates, healthy fats, and plenty of fruits and vegetables. Finally, getting adequate sleep and managing stress are also important factors in maintaining and increasing lean body mass. Sleep is crucial for muscle recovery, and chronic stress can lead to the breakdown of muscle tissue.
While 7-keto-DHEA is marketed as a weight loss supplement, its effects on lean body mass are not well studied. However, it is believed that 7-keto-DHEA may help preserve or increase lean body mass due to its thermogenic properties. In other words, it may increase the body's metabolism and promote the burning of fat while preserving muscle mass. This is supported by a study that found a significant weight loss in participants taking 7-keto-DHEA, with a greater percentage of fat loss compared to those in the placebo group. However, more research is needed to confirm these effects, especially regarding its impact on lean body mass specifically.
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Thyroid function
The thyroid gland is regulated by the brain through a negative feedback loop, similar to the process that controls DHEA production. This means that issues with the adrenal glands, which produce DHEA, can also impact thyroid function. Thyroid conditions can, in turn, affect DHEA levels. For example, one study showed that individuals with hypothyroidism had significantly lower levels of DHEA, DHEA-S, and PREG-S compared to those with hyperthyroidism.
The thermogenic properties of 7-keto DHEA, which increase metabolism and promote weight loss, are similar to those of thyroid hormones. 7-keto DHEA has been shown to increase the levels of certain enzymes, such as mitochondrial sn-glycerol-3-phosphate dehydrogenase (mGPDH) and cytosolic malic enzyme, which are also enhanced by thyroid hormones. This suggests a potential link between 7-keto DHEA and thyroid function.
Additionally, when applied to the skin as a gel, 7-keto DHEA has been found to affect thyroid function in men. However, the specific impact on thyroid function is not yet clear, and more research is needed to understand how it affects women.
Before taking 7-keto DHEA, it is recommended to have an evaluation that includes a physical exam and lab tests to determine hormone levels and thyroid function. This is especially important for individuals with a sluggish thyroid gland, as treating this condition may be sufficient to address weight loss concerns. The TSH (Thyroid Stimulation Hormone) Test is commonly used to assess thyroid function, but it is important to also measure Free T3 levels, as this is the active form of thyroid hormone.
In conclusion, while the specific relationship between 7-keto DHEA and thyroid function requires further research, there is evidence of a potential link between the two. Individuals considering taking 7-keto DHEA should consult with a healthcare professional to ensure their thyroid function is properly evaluated and any potential risks are addressed.
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Immune system
7-Keto DHEA is a supplement that is often promoted as a metabolism booster and is said to have a positive impact on the immune system. It is a natural byproduct of DHEA (dehydroepiandrosterone), a "parent hormone" produced by glands near the kidneys. Unlike DHEA, 7-Keto DHEA is not converted into sex hormones like androgen and estrogen. Instead, it plays a role in metabolism and fat burning by increasing the production of white blood cells, which are crucial for immune function.
The impact of 7-Keto DHEA on the immune system is suggested by its ability to increase the production of white blood cells, which are essential for fighting infections and diseases. Additionally, 7-Keto DHEA has been found to boost the body's ability to produce interleukin-2 (IL2), a type of cytokine that is vital for immune response and regulating the immune system.
While there is some evidence to support the immune-boosting properties of 7-Keto DHEA, more research is needed to confirm its effectiveness. The available studies suggest that 7-Keto DHEA may enhance immune function by increasing the production of white blood cells and certain cytokines. However, the full extent of its impact on the immune system and overall health is yet to be determined.
It is important to note that the effectiveness of 7-Keto DHEA may vary among individuals, and there is limited information on its safety during pregnancy and breastfeeding. Therefore, it is always advisable to consult a healthcare professional before taking any supplements, especially for those with specific health conditions or concerns.
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Memory
One of the key indicators of 7-Keto DHEA's effectiveness is its impact on cognitive function, particularly memory. This is because the supplement has a unique ability to enhance and support brain health. So, how exactly does 7-Keto DHEA influence memory, and what changes might you expect to notice?
The first sign that 7-Keto DHEA is positively affecting your memory could be an improvement in your ability to recall words, names, and everyday items. You might find yourself no longer struggling to find the right word during a conversation or recall the name of someone you met recently. This enhanced recall ability often extends to improved memory for appointments, tasks, and social events, leading to better time management and organization.
Another area of memory that 7-Keto DHEA can influence is recognition memory. This is the type of memory that allows you to recognize familiar faces, places, and objects. With improved recognition memory, you might find yourself more easily navigating familiar routes or quickly identifying a song you haven't heard in years. This type of memory enhancement can lead to a heightened sense of familiarity and comfort with your surroundings.
The supplement's impact on memory also extends to episodic memory, which involves the recollection of specific events and experiences from your past. With improved episodic memory, you might find yourself reminiscing about old times more vividly and frequently, recalling specific details, emotions, and sensations associated with those memories. This can lead to a deeper connection with your past and a greater sense of self-awareness.
Finally, 7-Keto DHEA can also enhance your working memory, which is the ability to hold and manipulate information in your mind over short periods. Improved working memory can lead to better focus, decision-making, and problem-solving abilities. You might find it easier to follow complex instructions, manage multiple tasks simultaneously, or perform mental calculations.
The memory-enhancing effects of 7-Keto DHEA typically become noticeable within the first few weeks to months of consistent supplementation. However, it's important to remember that individual results may vary, and combining supplementation with a healthy lifestyle, including mental exercises and brain-healthy foods, can further enhance its benefits.
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Frequently asked questions
7-keto DHEA is a by-product of dehydroepiandrosterone (DHEA), a chemical formed in the body by glands near the kidneys. Unlike DHEA, 7-keto DHEA is not converted to steroid hormones such as androgen and estrogen.
7-keto DHEA is thought to promote weight loss by speeding up the body's metabolism and increasing heat production through a process called thermogenesis. It is also claimed to improve lean body mass, build muscle, increase thyroid gland activity, boost the immune system, enhance memory, and slow aging.
7-keto DHEA is likely safe and has a low risk of serious side effects when taken orally for up to eight weeks. However, there is limited research on the long-term effects of this supplement, and it is not recommended for use during pregnancy or breastfeeding due to a lack of available information.