Using 7-Keto Dhea: Benefits And Effective Ways

7-Keto DHEA is a non-hormonal metabolite of DHEA, a parent hormone produced by glands near the kidneys. Unlike DHEA, 7-Keto DHEA is not converted into steroid hormones such as androgen and estrogen. It is often marketed as a dietary supplement for weight loss and is thought to work by increasing metabolic rate. However, there is limited evidence supporting its efficacy, and the long-term safety of 7-Keto DHEA has not been established. The appropriate dosage is also not yet known, but it is recommended that those wishing to take it consult a physician, particularly if they have a thyroid disorder or are taking thyroid medication.

7-Keto DHEA dosage

7-Keto DHEA is a supplement that is often used to boost weight loss and may provide some cognitive benefits. It is a metabolite of the parent hormone dehydroepiandrosterone (DHEA). 7-Keto DHEA is commonly sold in 25 mg and 100 mg pills, but it can also be found in powder supplement form or as a topical gel, either on its own or combined with other ingredients.

The dosage of 200 mg per day for 4-8 weeks was found to be safe and produced mild benefits in one study. In another study, older men received a lower dose of 25 mg of 7-keto daily in the form of a gel applied to the skin. A dosage of 25-150 mg of 7-keto per day was found to be safe and moderately effective in women with PTSD.

In terms of weight loss, one study found that 33 overweight adults who received 7-Keto DHEA supplements (200 mg/day) for 8 weeks, along with diet and exercise, lost more weight than with diet and exercise alone, with no adverse effects. Another study in overweight adults found that the addition of 7-Keto-DHEA (100 mg B.I.D.) resulted in significant reductions in body weight and body fat compared to a placebo, during an eight-week intervention with exercise and a reduced-calorie diet.

It is important to note that the optimal dosage of 7-Keto DHEA is still uncertain, as very limited studies have been conducted using higher or lower doses. Additionally, 7-Keto DHEA is not recommended for women who are pregnant or breastfeeding due to inconclusive results and a lack of tested information.

7-Keto DHEA and weight loss

7-Keto-DHEA is a supplement that may increase your metabolism and lead to weight loss. It is a naturally occurring metabolite of dehydroepiandrosterone (DHEA), a hormone produced by glands near the kidneys. Unlike DHEA, 7-Keto-DHEA is not converted to steroid hormones such as androgen and estrogen.

Early studies suggest that DHEA prevents fat gain due to its thermogenic, or heat-producing, properties. One test-tube study found that 7-Keto-DHEA was two-and-a-half times more thermogenic than DHEA. This finding led researchers to begin testing the thermogenic properties of 7-Keto-DHEA in humans.

To date, only two studies have looked at the effects of 7-Keto-DHEA on metabolism. In the first study, researchers found that participants who were overweight and received a supplement containing 100 mg of 7-Keto-DHEA lost significantly more weight than those given a placebo, but there was no difference in basal metabolic rate (BMR) between the two groups. However, in another study, 7-Keto-DHEA was found to increase the resting metabolic rate (RMR) of people who were overweight.

In one eight-week study, participants who received 200 mg per day of 7-Keto-DHEA lost 6.3 pounds, compared to a 2.1-pound weight loss in the placebo group. In a similar study, researchers looked at the effects of a supplement containing 7-Keto-DHEA combined with seven other ingredients. While all participants adhered to a reduced-calorie diet and exercised three days per week, those who received the supplement lost significantly more weight than people in the placebo group.

While 7-Keto-DHEA is likely safe and has a low risk of serious side effects, there are some considerations to keep in mind. 7-Keto-DHEA supplements have been suggested to trigger positive tests for performance-enhancing drugs, and are banned by the World Anti-Doping Association (WADA). Additionally, 7-Keto-DHEA may influence hormones in men when applied to the skin as a gel.

Overall, 7-Keto-DHEA is a popular supplement thought to boost metabolism and aid weight loss. However, the evidence is still limited, and more research is needed to determine its effectiveness and safety.

7-Keto DHEA side effects

7-Keto DHEA is generally well-tolerated and has a low risk of serious side effects. However, some adverse effects have been reported in studies, including heartburn, a metallic taste in the mouth, and nausea.

One study showed that the supplement was well-tolerated in men at doses of up to 200 mg per day for four weeks. The optimal dosing schedule and overall dose of 7-Keto DHEA are not yet known, but a typical supplemental dosage is 200-400 mg daily in two divided doses.

It is important to note that 7-Keto DHEA supplements have been suggested to trigger positive tests for performance-enhancing drugs. As a result, the World Anti-Doping Association (WADA) has listed the supplement as a prohibited anabolic agent. If you are involved in sports and subject to performance-enhancing drug tests, you should avoid taking 7-Keto DHEA supplements.

Additionally, while 7-Keto DHEA does not affect hormone levels when taken orally, it may influence them if applied to the skin as a gel. Several studies have shown that when applied to the skin, 7-Keto DHEA can affect sex hormones, cholesterol, and thyroid function in men. The effects of 7-Keto DHEA gel on women are still unknown.

For these reasons, it is important to consult with a doctor or pharmacist before trying 7-Keto DHEA, especially if you are considering using it in gel form.

7-Keto DHEA safety

7-Keto DHEA is a non-hormonal metabolite of DHEA, which is a "parent hormone" produced by glands near the kidneys. Unlike DHEA, 7-Keto DHEA is not converted to steroid hormones such as androgen and estrogen. It is often marketed as a dietary supplement to support weight loss, with some studies showing promising results. However, it is important to note that the long-term safety of 7-Keto DHEA has not been established.

Safety Precautions

7-Keto DHEA is possibly safe when taken by mouth for up to 8 weeks and might cause mild side effects such as nausea, dizziness, or low blood pressure in some people. It is not recommended for those who are pregnant or breastfeeding, or under the age of 18. Additionally, those with a family history of prostate cancer, prostate enlargement, heart disease, or low HDL cholesterol should consult a healthcare professional before use. It is also important to consult a physician if one has a thyroid disorder or is taking thyroid medication, as 7-Keto DHEA may increase levels of the thyroid hormone T3.

Drug Interactions

There are no known drug interactions with 7-Keto DHEA as of the last update. However, it is always recommended to consult a doctor or pharmacist before adding any new supplement to one's regimen.

7-Keto DHEA and metabolism

7-Keto DHEA is a non-hormonal metabolite of DHEA, a "parent hormone" produced by glands near the kidneys. Unlike DHEA, 7-Keto DHEA is not converted into testosterone or estrogen by the human body. This minimises the potential for androgenic and estrogenic activity.

7-Keto DHEA is often used as a fat loss agent, as it may increase the metabolic rate. It promotes metabolic support by enhancing DHEA absorption. It is also believed to have anti-cortisol mechanisms, as the enzymes that activate cortisol are the same that interconvert these oxygenated metabolites.

Studies have shown that 7-Keto DHEA increases the metabolic rate during caloric restriction, which is secondary to reducing the rate of metabolic rate decline associated with dieting. This thermogenic effect may contribute to increased basal metabolism, supporting a healthy lean/adipose ratio.

However, the benefits of 7-Keto DHEA supplementation are not definitively established. The current evidence is mixed and limited by factors such as small sample sizes, short study durations, and a lack of diversity in the study populations. The US Food and Drug Administration (FDA) has not added 7-Keto DHEA to the list of bulk drug substances due to a lack of clinical evidence regarding its safety and efficacy.

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