
The Bredesen Diet, also known as KetoFLEX 12/3, is a brain-healthy diet developed by Dr. Dale Bredesen, a neurologist and author of the book, 'The End of Alzheimer's'. The diet is a modified keto diet designed to aid in preventing and reversing cognitive decline by promoting brain function and reducing inflammation. It involves eating whole foods, including many plant-based foods, healthy fats, and omega-3-rich proteins, while limiting simple carbohydrates and high-glycemic foods that can cause inflammation. The diet also includes intermittent fasting, with a minimum 12-hour fast, including 3 hours before bed. With the Bredesen Diet's focus on plant-based, nutrient-dense, and whole foods, the question arises: is flax meal allowed on this dietary regimen?
| Characteristics | Values |
|---|---|
| Creator | Dr. Dale Bredesen |
| Type of diet | KetoFLEX 12/3, a mildly ketogenic, plant-rich, highly nutritive diet |
| Fasting | Minimum 12 hours, including 3 hours before bed |
| Food to eat | Fresh produce, seafood, pastured eggs, poultry, meats from local farms, olive oil, avocados, nuts, seeds, berries, leafy greens, cruciferous vegetables, green tea, matcha |
| Food to avoid | Refined carbohydrates, added sugars, red meat, antibiotic and hormone-laden dairy products, processed foods, fruit juices, gluten, starchy vegetables |
| Goal | Reduce inflammation, promote brain function, prevent and reverse cognitive decline |
| Side effects | Improved overall health and protection from chronic diseases |
| Criticisms | Costly regimens of dietary supplements, lack of rigorous scientific evidence supporting the program's claims |
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What You'll Learn

Flax meal and the Bredesen Protocol
The Bredesen Protocol, also known as the "Alzheimer's Diet", was developed by Dr. Dale Bredesen, a neurologist and author of the book "The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline". The protocol is a highly individualized treatment approach that aims to improve brain functioning, address cognitive decline, and even regenerate the brain. It involves adopting specific dietary and lifestyle habits that have been clinically shown to benefit Alzheimer's patients.
The Bredesen Protocol includes the KetoFLEX 12/3 diet, a modified ketogenic, plant-rich, and highly nutritive dietary approach. This diet emphasizes the consumption of whole foods, local and seasonal produce, and a rainbow variety of non-starchy vegetables. It encourages adequate protein intake and generous amounts of healthy fats, such as olive oil, avocados, nuts, seeds, and omega-3-rich proteins. The protocol recommends limiting simple carbohydrates, high-glycemic foods, gluten, dairy, and starchy vegetables, as they can cause inflammation.
Now, let's focus on flax meal in the context of the Bredesen Protocol. Flax meal, or ground flaxseed, is not explicitly mentioned in the sources outlining the Bredesen Protocol and KetoFLEX 12/3 diet. However, one source mentions a comment from an individual following a whole food plant-based diet, who consumes one tablespoon of ground flaxseed daily. This suggests that flax meal is compatible with the Bredesen Protocol and can be included as a source of healthy fats and omega-3 fatty acids.
When incorporating flax meal into the Bredesen Protocol, it is essential to do so in moderation and ensure it aligns with the overall principles of the diet. Flax meal can be used as a topping for non-starchy vegetables, added to smoothies or yogurt, or incorporated into baking recipes that use approved ingredients. It is always advisable to consult with a healthcare professional or a practitioner familiar with the Bredesen Protocol to ensure any dietary changes are safe and aligned with individual needs.
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The Bredesen Diet
The KetoFLEX 12/3 diet is a mildly ketogenic, plant-rich, and highly nutritious diet. It involves eating whole foods, including many plant-based foods, and emphasises the consumption of local, organic, and seasonal produce. The diet recommends a minimum of 12 hours of fasting, including 3 hours before bed, to achieve a state of ketosis, where the body uses dietary fat and breaks down stored fat as its primary source of fuel. This diet is flexible, allowing people to choose whether to include meat, and it does not require strict adherence to a specific number of carbohydrates per day. However, it generally recommends less than 60 grams of carbohydrates per day and suggests avoiding simple carbohydrates and high-glycemic foods, as they can cause inflammation.
The Bredesen Protocol, of which the KetoFLEX 12/3 diet is a part, takes a holistic approach to health. It addresses not only dietary changes but also physical and mental activity, stress reduction, and addressing pathogens and toxins. The protocol includes comprehensive testing of various biomarkers, such as glucose response, insulin levels, inflammatory status, and genetic variation, to develop individualised care plans. While the Bredesen Diet has received some criticism for its costly regimens of dietary supplements and the lack of rigorous scientific evidence supporting its claims, it offers a potential approach to preventing and addressing cognitive decline and Alzheimer's disease.
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Ketosis and the Dale Bredesen Diet
The Dale Bredesen Diet, also known as the KetoFLEX 12/3 diet, is a brain-healthy diet developed by Dr. Dale Bredesen, a world-class neurologist and neuroscientist. The diet is based on the idea of achieving a state of mild ketosis, where the body uses dietary and stored fat as its primary source of fuel, instead of carbohydrates. This metabolic state is believed to be beneficial for brain health and overall health.
Ketosis is achieved by consuming a high amount of healthy fats, moderate protein, and very low carbohydrates. The KetoFLEX 12/3 diet recommends a plant-rich, highly nutritive approach, emphasizing local, organic, and seasonal non-starchy vegetables, adequate protein sources, and generous amounts of healthy fats. This diet is combined with a minimum 12-hour nightly fast, including 3 hours before bed.
The goal of the Bredesen Diet is to reduce inflammation and promote brain function. Dr. Bredesen's research has shown that this diet can help prevent and reverse cognitive decline, improve brain functioning, and even regenerate the brain. The diet is particularly targeted at preventing and treating Alzheimer's disease, as evidenced by his book, "The End of Alzheimer's."
To support the transition into ketosis, the Bredesen Diet recommends taking exogenous ketones like MCT oil, ketone salts, or esters. Additionally, it is important to combine the diet with lifestyle changes such as optimized sleep, physical activity, stress management, and supplementation. The diet also emphasizes consuming whole foods in their natural state, similar to the Mediterranean diet, and avoiding processed foods, refined carbohydrates, added sugars, and excessive red meat.
In summary, the Dale Bredesen Diet, or KetoFLEX 12/3, is a mildly ketogenic, plant-based, and nutrient-dense dietary approach designed to optimize brain health and overall well-being. It involves achieving mild ketosis through a specific diet and fasting routine, along with lifestyle modifications, to reduce inflammation and enhance cognitive function.
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Benefits of the Dale Bredesen Diet
The Bredesen Protocol, also known as the "Alzheimer's Diet", was developed by Dr. Dale Bredesen of the Buck Institute for Research on Aging. It involves adopting dietary and lifestyle habits that have been clinically shown to benefit Alzheimer’s patients and reduce the risk of cognitive decline.
The protocol is based on Dr. Bredesen's research, which found that a highly-individualized treatment protocol with certain similar components can produce improvements in brain functioning and markers of cognitive decline and even regenerate the brain. The protocol involves comprehensive testing, including measuring glucose response, insulin levels, inflammatory status, genetic variation, gut integrity, and the blood-brain barrier.
The diet component of the protocol, KetoFLEX 12/3, is a mildly ketogenic, plant-rich, highly nutritive diet combined with a minimum 12-hour fast (including 3 hours before bed). It emphasizes eating whole foods that are closest to their natural state, like fresh produce, seafood, pastured eggs, poultry, and meats from local farms. It also includes healthy fats such as olive oil, avocados, nuts, and seeds, which are key staples of the Mediterranean diet.
The Bredesen Diet also recommends gradually introducing prebiotic and probiotic foods to improve gut health, as well as supplementing with nutrients such as ginkgo leaf extract, phosphatidylserine, and turmeric to promote brain function. Overall, the Bredesen Diet provides a guideline for healthy eating practices to reduce inflammation and promote brain function, with the potential to prevent and treat cognitive decline.
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Foods to avoid on the Dale Bredesen Diet
The Bredesen Diet, also known as the KetoFLEX 12/3 diet, is a brain-healthy diet developed by Dr. Dale Bredesen, a neurologist and author of the book "The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age". This diet aims to reduce inflammation, promote brain function and prevent cognitive decline.
The diet recommends eating whole foods that are closest to their natural state, such as:
- Fresh produce
- Seafood
- Pastured eggs
- Poultry
- Meats from local farms
It also suggests consuming 6-9 cups of non-starchy vegetables, healthy herbs, spices, and teas, like green tea or matcha.
Now, let's look at the foods to avoid on the Dale Bredesen Diet:
Refined Carbohydrates and Added Sugars
The typical Western diet often contains excessive amounts of refined carbohydrates and added sugars, which can cause inflammation and negatively impact brain health. These include foods such as baked goods, crackers, frozen dinners, breakfast cereals, and desserts.
Conventional Dairy Products
The diet advises eliminating conventional dairy products, as they can be laden with antibiotics and hormones, contributing to inflammation.
High-Mercury Fish
While the diet encourages the consumption of fish and seafood for their omega-3 content, it is important to avoid fish with high mercury levels. Refer to the acronym SMASH (salmon, mackerel, anchovies, sardines, and herring) for safer options.
Excessive Fruit Intake
Although fruits are included in the diet, it is important to monitor fruit portions, as they can be high in carbohydrates. Strawberries are believed to be among the lowest-carbohydrate options.
Grains
The Bredesen Diet recommends eliminating all grains from the diet, as they can contribute to inflammation and cognitive decline.
Processed Foods
Processed foods with added ingredients, such as baked goods, crackers, frozen dinners, and breakfast cereals, are discouraged due to their negative health effects.
Simple Carbohydrates
Simple carbohydrates, such as soda and desserts, have a high glycemic index and can cause a rapid increase in blood sugar levels. It is recommended to consume complex carbohydrates and foods with a lower glycemic index instead.
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Frequently asked questions
The Dale Bredesen diet, also known as the KetoFLEX 12/3 diet, is a plant-rich, highly nutritive diet that involves intermittent fasting for a minimum of 12 hours, including 3 hours before bed.
The Dale Bredesen diet focuses on eating whole foods closest to their natural state, such as fresh produce, seafood, poultry, and meats from local farms. It recommends a high intake of healthy fats and omega-3-rich proteins, and low-glycemic carbohydrates.
Yes, flax meal is allowed on the Dale Bredesen diet. In fact, one source mentions that a user of the diet consumes one tablespoon of ground flaxseed every day.
The Dale Bredesen diet aims to reduce inflammation, promote brain function and prevent cognitive decline.











































