7-Keto-DHEA is a by-product of dehydroepiandrosterone (DHEA), a chemical formed in the body by the adrenal glands near the kidneys. Unlike DHEA, 7-Keto-DHEA is not converted into hormones like androgen and estrogen. It is commercially advertised as a dietary supplement to support weight loss and is often used alongside a restricted-calorie diet and exercise. While some studies have shown that 7-Keto-DHEA may increase metabolism and lead to weight loss, there is insufficient evidence to rate its effectiveness, and more research is needed. It is possibly safe when used orally for up to 8 weeks, but there is limited information on its long-term effects.
Characteristics | Values |
---|---|
How it works | Speeds up the body's metabolism and converts more energy to heat instead of storing it as fat |
Who it's for | People who are obese, or those with low levels of DHEA |
How to take it | Orally, or applied to the skin |
Dosage | 100-200 mg per day |
Other uses | Improving lean body mass, increasing thyroid activity, boosting the immune system, enhancing memory, slowing aging |
Precautions | Not enough evidence to know if it's safe for use. Avoid during pregnancy and breastfeeding |
What You'll Learn
7-Keto-DHEA dosage
7-Keto-DHEA is a by-product of dehydroepiandrosterone (DHEA), a chemical produced by glands near the kidneys. Unlike DHEA, 7-Keto-DHEA is not converted into androgen or estrogen hormones. It is often taken to speed up metabolism and promote weight loss.
Dosage
The appropriate dosage of 7-Keto-DHEA depends on several factors, such as the user's age, health, and other conditions. The dosage also depends on the purpose of taking the supplement.
For weight loss, a double-blind study found that participants who took 100 mg of 7-Keto-DHEA twice daily for eight weeks, in conjunction with a diet and exercise program, lost more weight and lowered their body fat percentage compared to those taking a placebo. Another study found that a dosage of 200 mg per day for eight weeks resulted in an average weight loss of 6.3 pounds.
It is important to note that there is currently insufficient information to determine the safe and appropriate dosage range for 7-Keto-DHEA. It is recommended to follow the directions on product labels and consult a healthcare professional before use.
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Weight loss claims
Some dieters claim that 7-KETO helps promote weight loss when used alongside a diet and exercise program. It is believed that 7-KETO might promote weight loss by speeding up the body's metabolism and converting more energy to heat instead of storing it as fat.
In one double-blind trial, participants were advised to exercise three times per week for 45 minutes and to eat an 1,800-calorie-per-day diet. Each person was given either a placebo or 100 mg of 7-KETO twice daily. After eight weeks, those receiving 7-KETO had lost more weight and lowered their percentage of body fat compared to those taking a placebo. However, it is important to note that the long-term safety of 7-KETO for humans has not been demonstrated, and there is a potential for adverse effects due to its chemical similarity to steroid hormones.
In another eight-week study, 30 overweight people on a calorie-restricted diet who exercised three days per week were given either 200 mg per day of 7-KETO or a placebo. The group receiving 7-KETO lost significantly more weight, with an average loss of 6.3 pounds compared to 2.1 pounds in the placebo group.
A few other studies have also investigated the effects of 7-KETO on weight loss, with mixed results. While some studies have shown a significant reduction in body weight, body fat percentage, and an increase in resting metabolic rate, others have found no significant differences in weight loss or basal metabolic rate.
Overall, while there is some evidence to suggest that 7-KETO may aid in weight loss, particularly when combined with a calorie-restricted diet and exercise, more research is needed to confirm its effectiveness and safety.
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Safety and side effects
7-Keto is generally considered safe and well-tolerated, with a low risk of serious side effects. However, there are some safety considerations and potential side effects to be aware of when taking 7-Keto for weight loss.
Short-Term Safety and Side Effects
When taken orally, 7-Keto is possibly safe for up to 8 weeks and is well-tolerated in the short term. One study showed that the supplement was well-tolerated in men at doses up to 200 mg per day for four weeks. However, some people have reported feeling "jittery" after taking as little as 100 mg of 7-Keto per day. Other reported side effects in both men and women include heartburn, a metallic taste, and nausea.
Long-Term Safety and Side Effects
The long-term safety of 7-Keto for humans has not been established. Due to its chemical similarity to steroid hormones, there is a potential for adverse effects with long-term use. Additionally, 7-Keto can increase thyroid hormone levels, which may have negative effects on the heart and promote bone loss. Rare side effects associated with increased thyroid hormone levels include sweating, insomnia, increased blood pressure and heart rate, and mood changes such as increased anxiety or irritability. People with pre-existing thyroid disease or taking thyroid medication are advised to consult a doctor before using 7-Keto.
Drug Interactions
7-Keto might interact with the metabolism of other steroids. High levels of 7-Keto can influence the conversion of cortisone to cortisol, and vice versa. Therefore, individuals taking cortisone-based medication should consult a doctor before using 7-Keto. Additionally, 7-Keto supplements have been known to trigger positive tests for performance-enhancing drugs, and it is listed as a prohibited anabolic agent by the World Anti-Doping Association (WADA).
Special Populations
There is limited information available on the safety of 7-Keto for pregnant or breastfeeding women. It is recommended to avoid using 7-Keto during pregnancy and breastfeeding due to a lack of sufficient safety data.
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Exercise and diet
Dieters who take 7-KETO supplements often do so in conjunction with a diet and exercise program. In one double-blind trial, participants were advised to exercise three times per week for 45 minutes and to eat an 1,800-calorie-per-day diet. In another study, participants were placed on a calorie-restricted diet and exercised three days per week.
In terms of diet, it is important to note that 7-KETO is not a substitute for a healthy diet and regular exercise. A well-rounded diet that includes a variety of nutrient-dense foods from all food groups is essential for overall health and can help support weight loss efforts.
It is recommended to focus on whole, unprocessed foods, such as fruits, vegetables, whole grains, lean proteins, and healthy fats. These foods provide the body with the nutrients it needs to function optimally and can help promote weight loss by keeping you feeling full and satisfied.
In addition to a healthy diet, regular exercise is crucial for weight loss and overall health. Aim for at least 150 minutes of moderate-intensity aerobic activity or 75 minutes of vigorous-intensity aerobic activity per week, as well as strength training at least twice a week.
It is worth noting that the combination of a calorie-restricted diet and exercise has been shown to result in significant weight loss when used in conjunction with 7-KETO. However, more research is needed to determine the long-term effects of this supplement.
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How it works
7-Keto-DHEA is a by-product of dehydroepiandrosterone (DHEA), a chemical produced by glands near the kidneys. Unlike DHEA, 7-Keto-DHEA is not converted into hormones like androgen and estrogen. Instead, it is believed to promote weight loss by increasing the body's metabolism and converting more energy into heat rather than storing it as fat.
Several studies have been conducted to test the effectiveness of 7-Keto-DHEA in weight loss. One study found that participants who took 200 mg of 7-Keto-DHEA daily for eight weeks, in conjunction with a calorie-restricted diet and exercise regimen, lost more weight than those in the placebo group. Another study found that participants who took 100 mg of 7-Keto-DHEA twice daily for eight weeks, while also adhering to an 1,800-calorie diet and exercising three times a week, lost more weight and lowered their body fat percentage compared to the placebo group.
In addition to its weight loss benefits, 7-Keto-DHEA is also believed to improve lean body mass, increase thyroid gland activity, boost the immune system, enhance memory, and slow ageing. However, it is important to note that there is currently insufficient evidence to support these claims, and more research is needed to fully understand the effectiveness and safety of 7-Keto-DHEA.
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Frequently asked questions
7-Keto-DHEA is a by-product of dehydroepiandrosterone (DHEA), a chemical produced by glands near the kidneys. Unlike DHEA, 7-Keto-DHEA is not converted into steroid hormones such as androgen and estrogen.
7-Keto-DHEA may promote weight loss by speeding up the body's metabolism and increasing heat production, a process known as thermogenesis. This can lead to increased fat burning and weight loss. However, more research is needed to confirm its effectiveness.
The recommended dosage of 7-Keto-DHEA varies depending on individual factors such as age, health status, and other conditions. Most supplements on the market contain 100 mg per serving, with a suggested intake of two servings per day with food. However, it is important to consult a healthcare professional before taking any supplements.