Niagen And Keto: A Healthy Combination?

Niagen is a supplement that contains nicotinamide riboside (NR), a precursor to nicotinamide adenine dinucleotide (NAD+). NAD+ is a coenzyme that helps the body produce cellular energy and is believed to support anti-aging. The keto diet, on the other hand, is a low-carb, high-fat diet that aims to put the body into a metabolic state called ketosis, where it burns fat for energy instead of carbohydrates. So, is Niagen okay for keto?

Niagen is generally recognized as safe (GRAS) by the FDA and is allowed in food products. It has been studied in both animal and human clinical trials, with no serious adverse events reported. While the long-term effects of Niagen supplementation are still unknown, short-term supplementation is considered safe.

On the keto diet, it is important to monitor carbohydrate intake and choose foods that are low in carbs and high in fats. Niagen, being a supplement, does not contain any carbohydrates and is high in fat, making it compatible with the keto diet.

Therefore, based on the available information, Niagen can be considered okay for keto. However, it is always recommended to consult with a healthcare professional before starting any new supplement, especially if you have any health concerns or are taking medications.

Niagen is a supplement that boosts NAD+ levels in the body

Tru Niagen is a patented form of NR and a precursor to NAD+. It crosses the cell membrane to efficiently increase NAD+ levels, according to some research. The supplement is generally recognized as safe (GRAS) by the FDA. It is NSF for Sport certified, meaning it does not contain any banned substances.

According to a 2019 study, Niagen is safe for consumption in dosages of up to 2,000mg a day. However, the long-term effects of the supplement are still unknown. While short-term supplementation is considered safe, the effects of long-term use are yet to be determined.

NAD+ is a coenzyme that helps with cellular energy production and repair

Niagen is a crystal form of NR chloride that is generally recognized as safe (GRAS) for use in foods and dietary supplements. It is a precursor to NAD+, a coenzyme that helps with cellular energy production and repair. NAD+ plays a pivotal role in energy metabolism pathways, including glycolysis, the TCA cycle, OXPHOS, FAO, and alcohol (ethanol) metabolism. It is a cofactor or substrate for biochemical reactions, with more than 300 enzymes relying on it for their activity. NAD+ is also involved in the maintenance and repair of DNA, chromatin remodelling, and autophagy. These functions are critical for maintaining tissue and metabolic homeostasis and healthy ageing.

NAD+ is a key player in cellular energy metabolism. As a coenzyme, it facilitates the enzymatic reactions involved in glycolysis, which is the process of breaking down glucose to release energy. NAD+ is reduced to NADH during this process, and the NADH molecule then drives the production of ATP, the cell's primary energy source. This transfer of electrons from NAD+ to NADH is fundamental to cellular respiration and energy production.

Beyond its role in energy production, NAD+ is also essential for maintaining and repairing DNA. It serves as a nucleotide analog in DNA ligation, protecting RNA from degradation and ensuring the stability and integrity of our genetic material. NAD+ is a co-substrate for enzymes such as PARPs, which signal DNA damage and assemble repair machinery. By maintaining healthy DNA, NAD+ helps prevent ageing-associated diseases and promotes healthy cellular function.

Additionally, NAD+ influences cellular senescence and immune cell function. As we age, our NAD+ levels naturally decline, impacting critical cellular processes. This decline in NAD+ levels has been linked to various ageing-associated diseases, including cognitive decline, cancer, metabolic disease, and frailty. However, by restoring NAD+ levels through supplements like Niagen, it may be possible to slow down or even reverse some of these ageing-related issues.

In summary, NAD+ is a crucial coenzyme that facilitates cellular energy production through its role in metabolic pathways and redox reactions. It is also essential for DNA maintenance and repair, chromatin remodelling, and maintaining overall cellular health. By supporting healthy ageing and protecting against ageing-associated diseases, NAD+ plays a vital role in our body's functionality and longevity.

Niagen is generally recognised as safe (GRAS) by the FDA

Niagen is a form of vitamin B3 known as nicotinamide riboside (NR) and is available as a supplement called Tru Niagen. It is a precursor to nicotinamide adenine dinucleotide (NAD+), which is believed to support anti-aging.

A crystalline form of NR chloride, Niagen has been evaluated in a battery of preclinical studies, including a bacterial reverse mutagenesis assay, an in vitro chromosome aberration assay, an in vivo micronucleus assay, and acute, 14-day and 90-day rat toxicology. In the 90-day toxicology study, NR had a similar toxicity profile to NAM at equimolar doses, with a no-observed-adverse-effect level (NOAEL) of 300 mg/kg/day.

While short-term supplementation with Tru Niagen is considered safe, the effects of long-term supplementation are unknown and require further research.

Niagen is NSF-certified for sport, meaning it does not contain any banned substances

Niagen is a patented form of nicotinamide riboside (NR), a form of vitamin B3. It is a precursor to nicotinamide adenine dinucleotide (NAD+), which is believed to support anti-aging and healthy aging. NAD+ is a coenzyme that helps your cells generate the energy that powers all the functions in your body.

Niagen has been deemed safe for consumption by adults when taken as recommended. It has been tested in multiple clinical studies and has been found to be safe and well-tolerated, even in high doses. It does not lead to any adverse effects and is not known to negatively interact with medications.

The Food and Drug Administration (FDA) does not regulate nutrients or supplements in the same way that it regulates pharmaceuticals. However, Niagen has received two FDA notifications, which means that the parent company has provided extensive safety data to the FDA, and the FDA has raised no objections to its use.

In addition to FDA compliance, Niagen has also undergone rigorous testing and quality control to receive NSF certification. This certification assures that the product is safe, properly labelled, and free of banned substances, making it a safe and reliable option for consumers.

Niagen may support the heart, brain, muscles, and immune system

Niagen is a form of vitamin B3 known as nicotinamide riboside (NR). It is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme that supports the body in producing cellular energy. NAD+ also plays a role in creating protein and helps repair cells and DNA.

NAD+ levels decline as we age, and this decline may be linked to age-related diseases and dysfunctions. Tru Niagen is a supplement that contains Niagen and is believed to support healthy aging, as well as brain, heart, muscle, immune, and cellular health.

Niagen May Support the Heart

Tru Niagen may help fuel heart cells with NAD+-boosted cellular energy and repair. A mouse model study found that nicotinamide riboside prevented heart failure.

Niagen May Support the Brain

Tru Niagen may support brain cells with the essential energy and repair they need. NAD+ is vital for cells' survival and function, fuelling processes like energy production and cellular repair.

Niagen May Support the Muscles

Tru Niagen may help energize and repair muscle cells, supporting performance and recovery.

Niagen May Support the Immune System

Tru Niagen may help boost immunity and resilience during times of immune stress. NAD+ is vital to systemic homeostasis, and declining levels may lead to age-related health issues.

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