
Proteinuria is a common issue in dogs, characterised by excess protein in their urine. It is usually indicative of an underlying condition, such as kidney disease, infections, inflammation, or high blood pressure. The treatment and prognosis of proteinuria depend on the underlying cause. If your dog has been diagnosed with proteinuria, it is important to consult a veterinarian to determine the best course of treatment, which may include medication and dietary changes. Dietary adjustments typically involve a low-protein, restricted-sodium, and omega-3 fatty acid-supplemented diet.
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What You'll Learn

A low-protein diet is key
Proteinuria is a condition where there is excess protein in a dog's urine. It is usually an indication of an underlying condition, the most common of which is kidney disease. Other causes include infections, inflammation, bleeding along the urinary tract, tumours, high blood pressure, lower urinary tract disease, and reproductive tract disease.
Commercial renal diets for dogs are available and are typically moderately restricted in protein content. These diets are designed to improve renal function and reduce proteinuria. It is important to note that too severe a restriction of protein intake can lead to weight loss and decreased plasma protein concentration, so it is crucial to consult a veterinarian to determine the appropriate level of protein restriction for your dog's specific needs.
In addition to a low-protein diet, other treatments for proteinuria may include medications such as antibiotics for urinary tract infections, high blood pressure medications, diuretics, and immunosuppressants in some cases. It is important to work closely with your veterinarian to develop a comprehensive treatment plan that addresses the underlying cause of proteinuria and effectively manages the condition.
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Treat the underlying cause
Proteinuria in dogs means there is excess protein in their urine. While dogs usually have a small amount of protein in their urine, excess protein can be a sign of an underlying condition. The most common causes of proteinuria include kidney disease, infections, inflammation, bleeding along the urinary tract, tumours, high blood pressure, and other conditions.
Treating the underlying cause of proteinuria is key to resolving the issue. For example, in cases of lower urinary tract infections, the condition can be treated relatively easily with antibiotics, and the proteinuria will go away.
Chronic causes of proteinuria, such as inflammatory bowel disease, Cushing's disease, or diabetes mellitus, may require long-term treatment. In these cases, the veterinarian will try to stabilize the disease and prevent long-term kidney damage.
In cases of severe kidney disease, such as severe inherited kidney disorder, cancer in the kidney, or kidney failure, the disease may not be able to be stabilized or may only be stabilized for a short time.
If your dog has been prescribed a special diet, they may show disinterest in the new food due to its lack of flavour. Consult your veterinarian on how to address this, as you may be able to enhance the flavour with tuna juice or another liquid.
It is important to note that proteinuria can be a negative prognostic indicator for dogs with chronic kidney disease, so persistent proteinuria should be taken seriously, regardless of its severity.
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Medication and prescription diets
Medication
If your dog has proteinuria, your vet will first identify the underlying cause through additional tests and a detailed health history. Once the cause is determined, your vet can develop a treatment plan. For example, if your dog has a blood clot, they might be prescribed a very low dose of aspirin or clopidogrel, a blood thinner.
If your dog has kidney disease, your vet will create a treatment plan to relieve symptoms and restore your dog's quality of life. This can include regular testing to monitor kidney function and medications that reduce pressure on the kidneys and help them function better. Common medications include high blood pressure medications, such as amlodipine and telmisartan, and possibly diuretics like furosemide or spironolactone, if edema is present. Antibiotics may also be prescribed if your dog has a urinary tract infection.
In cases of glomerular disease with severe proteinuria, hypoalbuminemia, or significant azotemia, immunosuppressive therapy may be considered to treat immune complex glomerulonephritis. The treatment of choice for glomerulonephritis in dogs is mycophenolate, given at a dose of 10 mg/kg every 12 hours. Prednisone may also be used as an induction agent in some severe cases, although prolonged therapy is not recommended due to potential side effects and worsening of proteinuria.
Prescription Diets
Your dog may also be prescribed a special diet with low sodium, low protein, and omega-3 fatty acids. This type of diet has been shown to improve UPC (Urine Protein Creatinine ratio) and blood pressure in dogs with proteinuria who are also receiving medical therapy.
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Keep your dog hydrated
Proteinuria in dogs refers to high levels of protein in a dog's urine. It is often a symptom of an underlying condition, such as kidney disease, infections, inflammation, or tumours. To manage proteinuria, it is important to identify and treat the underlying cause. In some cases, a special diet with low sodium, low protein, and omega-3 fatty acids may be prescribed by a veterinarian.
Now, onto keeping your dog well-hydrated! Proper hydration is crucial for your dog's health and overall well-being. Water plays a vital role in supporting organ function, aiding digestion, promoting good urinary tract health, and regulating body temperature. Here are some tips to ensure your dog stays hydrated:
Multiple Water Sources:
Place water bowls or fountains in various areas of your home and yard. This ensures easy access to water for your dog, especially if you have a large house or yard. Having multiple water sources encourages your dog to drink more. Don't forget to keep the water fresh and clean!
Use Different Types of Bowls:
Consider using stainless steel or ceramic bowls as they are easier to clean and less likely to harbour bacteria. For larger dog breeds, opt for bigger bowls or self-filling water fountains. Smaller dogs may prefer a water dispenser with a smaller opening.
Add Water to Food:
You can increase your dog's fluid intake by adding water to their food. This is especially beneficial for dogs who are picky drinkers. When adding water to dry or wet food, use lukewarm water. For canned food, be more generous with the amount of water added.
Encourage Water Consumption:
Make hydration fun and engaging for your dog! Use interactive toys that dispense water or create frozen treats with dog-friendly broth or fruit puree. You can also offer ice chips as a refreshing treat during hot weather.
Monitor Water Intake:
Keep an eye on your dog's water consumption, especially during hot weather or increased physical activity. As a general rule, dogs should drink approximately one ounce of water per pound of body weight each day. However, active dogs or those in hot climates may need more. Consult your veterinarian if you notice excessive water intake or signs of dehydration, such as lethargy, dry gums, or sunken eyes.
Provide Water on the Go:
When going outdoors or exercising with your dog, remember to carry a collapsible water bowl and a bottle of water. This ensures your dog can stay hydrated even when away from home. Always bring water when travelling with your dog, as not all locations may have readily available drinking sources.
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Monitor their recovery
Proteinuria is a common issue in dogs, and it can be a sign of underlying conditions such as kidney disease, infections, inflammation, or bleeding along the urinary tract. The first step in managing proteinuria is to identify and address the underlying cause. This often involves a special diet and medications prescribed by your veterinarian.
Monitoring your dog's recovery from proteinuria is crucial to ensure the treatment's effectiveness and your dog's overall health and well-being. Here are some key aspects of monitoring their recovery:
Regular Urine Testing: Collecting urine samples from your dog at regular intervals will help monitor the levels of protein in their urine. This is a non-invasive method to track the progress of the treatment. Typically, urine samples are tested at the vet's office, and your veterinarian will advise you on the frequency of testing.
Blood Work and Biochemical Profile: Regular blood tests will help monitor your dog's overall health during recovery. These tests can include complete blood counts, blood chemistry profiles, and electrolyte levels. Monitoring creatinine, potassium, and blood pressure is especially important, with the recommended frequency being 5-7 days after initiating treatment and each time the dosage changes. Monitoring blood pressure is crucial, as high blood pressure can be both a cause and an effect of proteinuria.
Physical Examinations: Routine physical examinations by your veterinarian will help assess your dog's overall health and monitor for any changes in their condition. This includes checking for edema or swelling in the legs, chest, or abdomen, which could indicate fluid retention and be a symptom of proteinuria or other underlying conditions.
Ultrasound and Imaging: Ultrasound scans and other imaging techniques can be used to examine your dog's internal organs, including the kidneys, to check for any structural abnormalities or changes during the recovery process.
Symptom Monitoring: Keep a close eye on your dog's daily activities and behaviour. Monitor their energy levels, appetite, water intake, and urination patterns. Look out for any unusual symptoms such as lethargy, increased thirst, or difficulty breathing, as these could indicate a relapse or an underlying condition that requires immediate veterinary attention.
Medication Adjustments: Based on the results of the above monitoring methods, your veterinarian may adjust the dosage or type of medication to ensure optimal treatment. It is important to follow their instructions and administer the medications as directed.
Remember, the recovery process for proteinuria will depend on the underlying cause and the severity of the condition. Work closely with your veterinarian to develop a tailored treatment and monitoring plan for your dog's specific needs.
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Frequently asked questions
Proteinuria is when there is excess protein in a dog's urine, which can be indicative of an underlying condition such as kidney disease.
In many cases, dogs with proteinuria do not show any symptoms at all. However, if kidney disease is the cause, symptoms can include lethargy and increased thirst.
A low-protein diet is recommended for dogs with proteinuria. Commercial renal diets are available that are moderately restricted in protein content and also contain restricted amounts of sodium.
Treatment will depend on the underlying cause of the proteinuria. If it is caused by kidney disease, your vet may recommend medications to reduce pressure on the kidneys and help them function better. Angiotensin-converting enzyme (ACE) inhibitors can also help to reduce proteinuria.
Proteinuria can be detected through a urine protein: creatinine ratio (UPC) test. A value above 0.5 is considered abnormal and may indicate proteinuria.











































