
The blood type diet is based on the idea that your ABO blood type (A, B, AB, or O) affects your health and that you should eat according to your blood type for optimal health. The concept of secretors and non-secretors adds another layer of personalisation to this diet. A secretor is someone who expresses their blood type not only in their blood but also in other bodily fluids like saliva and mucus. This is determined by the presence of the FUT2 secretor gene, which can be identified through DNA testing kits. Secretor status is believed to impact digestion and susceptibility to certain diseases and viruses, such as norovirus. However, it is important to note that there is limited scientific evidence supporting the effectiveness of the blood type diet, and independent studies have failed to produce significant results.
| Characteristics | Values |
|---|---|
| Definition | Secretors are individuals whose blood type (A, B, AB, or O) is present in bodily tissues and fluids such as saliva and mucus. |
| Prevalence | 76.1% of the population are secretors, while 23.9% are non-secretors. |
| Genetic Cause | Secretor status is caused by a single gene, the FUT2 secretor gene. |
| Health Effects | Secretor status affects the type of bacteria in the gut microbiome and impacts susceptibility to certain viruses, such as norovirus. |
| Diet | The Blood Type Diet, popularized by Dr. Peter D'Adamo, recommends different foods based on secretor status. |
| Testing | Secretor status can be determined through DNA testing kits, saliva samples, or blood analysis. |
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What You'll Learn

Secretors and non-secretors have different food values
Secretor status refers to whether or not your blood type (A, B, AB, or O) is present in bodily fluids like saliva and mucus, in addition to being in your blood. This is determined by your genes, specifically the presence of the FUT2 secretor gene. If you are a secretor, your blood type will be present in these fluids, whereas if you are a non-secretor, it will not be.
The difference in secretor status can impact the types of bacteria in your gut microbiome, and your susceptibility to certain viruses. For example, non-secretors are less likely to get infected by certain intestinal viruses such as Norovirus and Rotavirus, as these viruses use blood group glycans to attach to and enter cells, and non-secretors do not have these glycans in their intestinal mucosa.
The concept of secretor status has been explored in the context of the Blood Type Diet, popularized by Dr. Peter D'Adamo. The diet is based on the idea that different blood types should consume different foods to optimize health. The introduction of secretor status adds another layer of personalization to the diet, as it is claimed that secretors and non-secretors can have different food values, even for staple foods.
However, it is important to note that there is limited scientific evidence supporting the Blood Type Diet. Independent studies have failed to show how secretor status affects digestion, and there is doubt about whether a diet should be based on blood type.
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Secretor status is determined by a single gene
Secretor status is an important consideration in the blood type diet. It refers to an individual's ability to secrete blood-type antigens into bodily fluids. Secretors have their blood type in other body fluids like saliva and mucus, in addition to their blood. Non-secretors, on the other hand, have little to no blood type antigens in these bodily fluids.
An individual's secretor status can be determined through DNA testing kits or blood analysis. It is believed that secretor status affects the type of bacteria in the gut microbiome and may impact digestion and immune response. However, the exact mechanisms and implications of secretor status are still not fully understood, and there is limited research on the effectiveness of the blood type diet.
In terms of the blood type diet, secretor status further personalizes the dietary recommendations for each blood type. It is claimed that secretors and non-secretors may have different food values, even for staple foods. This information is used to create individualized diet plans, with specific food ratios, for those following the blood type diet.
While the concept of secretor status adds a layer of personalization to the blood type diet, it is important to note that there is ongoing debate and skepticism surrounding the validity of this dietary approach. Some studies have failed to find evidence supporting the effectiveness of the blood type diet, and it is considered by some to be a dangerous myth.
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Secretors have a higher prevalence of Bifidobacteria in their gut microbiome
Secretor status is a term used to describe whether or not an individual's blood type is present in their bodily fluids, such as saliva and mucus. Secretors are individuals whose blood type is present in these bodily fluids, while non-secretors have little to no blood type presence in these areas. This status is determined by the presence or absence of the FUT2 secretor gene, which can be identified through DNA testing kits or blood analysis.
The concept of secretor status is particularly relevant to the Blood Type Diet, a diet plan popularized by Dr. Peter D'Adamo. D'Adamo suggests that different blood types should consume different types of foods, and knowing one's secretor status further personalizes these dietary recommendations. According to D'Adamo, secretors and non-secretors may have different food values, even for staple foods.
While the Blood Type Diet has gained some traction, it is important to note that there is limited scientific evidence supporting the effectiveness of this diet. Independent studies have failed to produce significant results, and there is still much to be understood about how secretor status affects digestion and overall health.
Secretor status has been found to have an impact on the types of bacteria present in the gut microbiome. Specifically, secretors have been shown to have a higher prevalence of Bifidobacteria in their gut microbiome. Bifidobacteria are considered beneficial bacteria that help maintain a balanced immune system and aid in the breakdown of carbohydrates.
The higher prevalence of Bifidobacteria in secretors may be due to the presence of blood-type sugars in the intestine, which certain bacteria prefer to bind to or consume. This interaction between bacteria and blood-type sugars can influence digestion and nutrient production. However, more research is needed to fully understand the complex relationship between secretor status and the gut microbiome, as well as its potential implications for health and disease.
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Non-secretors are less susceptible to certain viruses
The human population can be categorized into secretors and non-secretors based on the presence or absence of A, B, and H antigens in bodily fluids and secretions, such as saliva, mucus, sweat, and tears. Secretors are individuals that secrete blood group antigens in their body fluids, while non-secretors do not. Non-secretors are less susceptible to certain viruses, such as the norovirus and rotavirus, which are common causes of the 'stomach flu'.
Non-secretors lack the FUT2 secretor gene, which means they do not secrete blood group antigens into their bodily fluids and tissues. This has implications for their gut microbiome and immune response. The gut microbiome plays a crucial role in viral infections, as certain intestinal viruses rely on the microbiota to infect the host. Non-secretors have been found to have reduced microbial richness compared to secretors, and this may contribute to their decreased susceptibility to certain viruses.
The norovirus, for example, uses blood group glycans to attach to intestinal cell walls and enter the body. Without these glycans, the norovirus cannot attach to the cells, and thus non-secretors are very unlikely to be infected by this virus. Similarly, non-secretors are less susceptible to the rotavirus, with infants who are non-secretors being significantly less likely to have symptomatic rotavirus infections.
In addition to their decreased susceptibility to certain viruses, non-secretors also have a lower risk of infection by H. pylori, a bacterium that can cause ulcers and stomach cancer. H. pylori attaches to the walls of the digestive tract and causes inflammation, but the free ABH antigens secreted by secretors prevent this attachment, giving them an advantage over non-secretors in this respect.
While non-secretors are less susceptible to certain viruses and bacterial infections, it is important to note that they may be at a health disadvantage in other ways. For example, non-secretors are more prone to influenza viruses, rhinoviruses, respiratory syncytial virus, and echinoviruses. They also have a higher risk of developing asthma, COPD, myocardial infarction, and chronic heart disease.
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Secretors have blood type antigens in their bodily tissues and fluids
Secretor status refers to the presence of blood type antigens in bodily tissues and fluids, such as saliva and mucus. This status is determined by the FUT2 gene, with secretors having the 'GA' or 'GG' variant and non-secretors having the 'AA' variant. Secretor status is believed to influence the types of bacteria in the gut microbiome, which can impact digestion and susceptibility to certain viruses and diseases. For example, non-secretors have a lower risk of norovirus infection due to the absence of specific blood group glycans that the virus uses to attach to and enter cells.
The concept of secretor status has been popularized by Dr. Peter D'Adamo, who introduced it in his book "Live Right 4 Your Type" as a companion to his Blood Type Diet. According to D'Adamo, an individual's secretor status can impact their dietary needs, with different foods being recommended or restricted based on this status. He offers personalized nutrition plans and sells supplements tailored to an individual's blood type and secretor status.
It is estimated that 80% of people are secretors, and this status is present across all ABO blood types (A, B, AB, and O). However, the frequency of secretors varies among different populations, with geographic and racial differences influencing the distribution. For example, a study found that 76.1% of a randomly selected group of healthy adults were secretors, with the highest frequency in blood group O individuals.
While the concept of secretor status and its impact on health and diet has gained some traction, it is important to note that there is limited scientific evidence supporting the Blood Type Diet. Independent studies have failed to replicate the claimed results, and there is doubt about whether an individual's blood type should be the primary basis for dietary recommendations.
In conclusion, while secretor status refers to the presence of blood type antigens in bodily tissues and fluids, the impact of this status on health and diet is not yet fully understood. More research is needed to determine the precise role that secretor status plays in digestion, disease susceptibility, and personalized nutrition.
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Frequently asked questions
A secretor is someone who has their blood type in bodily tissues and fluids such as saliva and mucus.
You can find out your secretor status by using a DNA testing kit or a saliva sample sent to a lab for testing. 23andMe also provides information on a genetic variant called rs601338, which is in the FUT2 gene. If you’re an ‘AA’, you’re a non-secretor. If you’re a ‘GA’ or ‘GG’, you’re a secretor.
Being a secretor or non-secretor is caused by one particular gene. It is believed that being a secretor or non-secretor can affect your digestion and your susceptibility to certain diseases and viruses. For example, non-secretors have a lower risk of Norovirus infection.






















