The ketogenic, or keto, diet is a trending diet that stresses the consumption of fats and proteins and severely limits carbohydrates and sugars. When the body doesn't have enough glucose to use for energy, it enters a state called ketogenesis, where ketone bodies are created from fatty acids and replace glucose as the body's primary source of energy. While the keto diet may be effective for some people living with Type 2 diabetes, it is not suitable for everyone.
The keto diet has been shown to be effective for blood sugar management and weight loss. However, it can also lead to a higher risk of hypoglycemia (low blood sugar), especially if medication and insulin intake are not balanced with eating patterns. Additionally, the keto diet can be notoriously difficult to stick to and may not be the best choice for long-term sustainability.
Recent research has also suggested that a 'cheat day' on the keto diet may have dangerous side effects, such as damaging blood vessels. This occurs due to the body's own metabolic response to spikes in blood sugar levels, which can lead to the death of blood vessel cells.
Therefore, while the keto diet may be beneficial for some, it is important to consult with a doctor or registered dietitian to determine if it is the right choice for your individual needs and goals.
Characteristics | Values |
---|---|
Effect on blood glucose | Lowers blood sugar |
Effect on weight | Leads to rapid weight loss |
Effect on diabetes | Can be used to manage Type 2 diabetes |
Effect on ketosis | Glucose and ketones are inversely related |
Effect on hypoglycaemia risk | Increases risk |
Effect on constipation | Can cause constipation |
Effect on nutrient intake | Can lead to lack of nutrients |
Effect on cardiovascular health | May damage blood vessels |
What You'll Learn
Glucose and ketones are inversely related
Glucose and ketones are indeed inversely related. Ketones are an alternative fuel to glucose for the human brain. When the body is deprived of glucose, it enters a state called ketogenesis, where ketone bodies are created from fatty acids and replace glucose as the body's primary source of energy.
Ketone levels are measured via one ketone body in the bloodstream, beta hydroxybutyrate (BHB). BHB levels within a 0.5 mmol/L - 1.0 mmol/L range is considered a "light nutritional ketosis." BHB levels within 1.0 mmol/L- 3.0 mmol/L is considered a more "optimal" ketosis.
The relationship between ketones and glucose is inverse. You can't really get a full picture of what is happening in your body unless you are monitoring your glucose as well.
- Lower glucose trends: Carbohydrates have the most influence on glucose levels. So, it makes sense that if you are following a zero to very low-carbohydrate diet, your glucose levels will remain more steady.
- Elevated fasting glucose levels: This is a very common trend that has been observed in individuals who have been following a strict keto diet for over a year. This is the body's way of assuring that glucose is present for organs that require it.
- High glucose spikes to small amounts of carbs: Individuals who follow a very low-carb diet may have lower insulin sensitivity compared to someone who consumes more carbs. Keto diets can lead to a temporary physiological insulin resistance, in which the body overreacts when carbs are introduced.
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Glucose is a form of sugar
Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using energy from sunlight. Glucose is used by plants to make cellulose—the most abundant carbohydrate in the world—for use in cell walls, and by all living organisms to make adenine triphosphate (ATP), which is used by the cell as energy.
Glucose is also naturally occurring and is found in its free state in fruits and other parts of plants. In animals, glucose is released from the breakdown of glycogen in a process known as glycogenolysis. Glucose circulates in the blood of animals as blood sugar.
The metabolic pathway that begins with molecules containing two to four carbon atoms and ends in the glucose molecule containing six carbon atoms is called gluconeogenesis and occurs in all living organisms. Glucose is also formed by the breakdown of polymeric forms of glucose like glycogen (in animals and mushrooms) or starch (in plants).
Glucose is a ubiquitous fuel in biology. It is used as an energy source in organisms, from bacteria to humans, through either aerobic respiration, anaerobic respiration (in bacteria), or fermentation. Glucose is the human body's key source of energy, providing about 3.75 kilocalories (16 kilojoules) of food energy per gram.
Breakdown of carbohydrates (e.g. starch) yields monosaccharides and disaccharides, most of which is glucose. Through glycolysis and later in the reactions of the citric acid cycle and oxidative phosphorylation, glucose is oxidized to eventually form carbon dioxide and water, yielding energy mostly in the form of adenosine triphosphate (ATP).
The insulin reaction, and other mechanisms, regulate the concentration of glucose in the blood. The physiological caloric value of glucose, depending on the source, is 16.2 kilojoules per gram or 15.7 kJ/g (3.74 kcal/g).
Glucose is extremely abundant and has been isolated from a variety of natural sources across the world.
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Ketosis is when the body runs out of glucose
Ketosis is a metabolic state that occurs when the body switches from burning glucose to burning fat for energy. This happens when the body does not have enough glucose from carbohydrates to use as fuel. Typically, the body breaks down carbohydrates into glucose and uses it as its main source of energy. However, when there is a very low intake of carbohydrates, the body's glucose stores are depleted, and it has to turn to burning fat for energy. This process is called ketosis.
During ketosis, the body breaks down fat into compounds called ketones, which become the main source of energy for the body and brain. Ketosis is characterised by elevated levels of ketones in the blood or urine. It is a natural and beneficial state for most people, and it can be induced by following a ketogenic or "keto" diet, which involves consuming a very low amount of carbohydrates and a high amount of fat.
When an individual's carbohydrate intake falls below 50 grams per day, their body will run out of glucose and enter ketosis within 3 to 4 days. The time it takes to enter ketosis can vary depending on factors such as physical activity level, insulin sensitivity, and genetics. For some people, it may take a week or longer.
Ketosis has several potential health benefits, including weight loss, increased energy, and improved metabolic health. It has been shown to be effective in treating and managing certain health conditions, such as epilepsy, Alzheimer's disease, and type 2 diabetes. However, the keto diet can also produce side effects, such as "keto flu," which includes symptoms like upset stomach, headache, and fatigue.
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Glucose is the body's preferred fuel source
The body can store some fuel in a form that offers muscles an immediate source of energy. However, the capacity of the body to store muscle and liver glycogen is limited to approximately 1,800 to 2,000 calories worth of energy, or enough fuel for 90 to 120 minutes of continuous, vigorous activity. As our muscle glycogen reserves continually decrease during exercise, blood glucose plays an increasingly important role in meeting the body's energy demands.
Glucose is also the brain's most significant source of energy, both at rest and during exercise. When blood glucose runs low, you can become irritable, disoriented, and lethargic, and you may be incapable of concentrating or performing even simple tasks.
The body can produce its own glucose, specifically from the liver. This process is known as gluconeogenesis, and it ensures our organs get the correct amount of glucose to function properly.
When the body doesn't have enough glucose available to use for energy, it enters a state called ketogenesis. In this state, ketone bodies are created from fatty acids and replace glucose as the body's primary source of energy.
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Glucose is necessary for survival
Glucose is a simple sugar that is necessary for survival. It is the preferred energy source for most cells in the body. When we eat, our body breaks down carbohydrates into glucose, which then enters the bloodstream. This process is essential for the brain, central nervous system, and red blood cells to function properly.
The body has a natural feedback mechanism that regulates glucose levels. When blood glucose levels increase, the pancreas releases insulin, which manages the rising blood sugar level by getting glucose into the cells. The cells then use glucose for energy or store it as fat for later use.
If the body does not produce enough insulin or becomes resistant to it, blood glucose levels can become too high or too low, leading to diabetes. In this case, medical treatment may be necessary to help process and regulate glucose.
While glucose is essential, the body does not need any added sugar to function healthily. Naturally occurring sugars in fruits, vegetables, and dairy products come with a variety of nutrients that the body needs to stay healthy. Added sugars, on the other hand, are typically found in processed foods and can lead to serious health problems such as diabetes, dementia, and obesity if consumed in excess.
Therefore, it is important to find a balance in the type and amount of sugar consumed. The American Diabetes Association recommends filling half of your plate with non-starchy, unprocessed vegetables and a quarter of your plate with minimally processed, fiber-rich carbohydrate foods. Limiting added sugars and highly processed carbohydrate foods is crucial for maintaining healthy glucose levels.
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Frequently asked questions
A recent study from the University of British Columbia in Okanagan, Canada, found that a single dose of carbohydrates after being on the keto diet may have dangerous side effects. The study found biomarkers in the blood suggesting that vessel walls were being damaged by the sudden spike in glucose.
Glucose and ketones are inversely related. As glucose rises, ketones fall, and vice versa. Therefore, measuring glucose levels on a ketogenic diet is crucial to understanding which foods will adversely impact ketosis.
The keto diet has been shown to be effective in lowering blood sugar levels and is often used to manage Type 2 diabetes. By severely restricting carbohydrates, the keto diet helps minimize the blood sugar response.
It is important to consult with a healthcare professional before starting any new diet, especially if you have a medical condition or are taking medication.