The ketogenic diet is a high-fat, low-carbohydrate diet that has been used to treat drug-resistant epilepsy for almost 100 years. In recent times, it has become popular for weight loss and is believed to have a range of health benefits, including improving heart health.
In people with heart failure, the muscle on the right or left side of the heart weakens, limiting the organ's ability to pump blood around the body. The leading causes of this are high blood pressure, diabetes, and ischemic heart disease. There is currently no cure, but medications and lifestyle changes can improve people's quality of life and increase their lifespan.
A study on mice showed that a high-fat, low-carb diet reversed heart failure in a mouse model of the condition. Another study showed that ketones can be utilised by the heart as an energy source in an unregulated manner, and that the capacity of the heart to oxidise ketones appears to be beneficial in patients with heart failure.
However, the ketogenic diet is associated with an increase in bad LDL cholesterol, which is linked to heart disease. It is also hard to follow and can be heavy on red meat and other fatty, processed, and salty foods that are notoriously unhealthy.
Overall, the ketogenic diet's long-term effects on cardiac function in the setting of heart failure are limited, and more studies are needed to determine the impact of a ketogenic diet on cardiovascular risk factors.
Characteristics | Values |
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Effectiveness | A high-fat, low-carb diet reversed heart failure in a mouse model of the condition. |
A 24-hour fast also led to improvements, mimicking the physiological effects of the diet. | |
The ketogenic diet has been linked to a range of possible health benefits, including supporting weight loss, improving heart health, and preventing seizures in some types of epilepsy. | |
The new research indicates that a ketogenic diet promotes the breakdown of fatty acids in heart muscle cells, producing an alternative fuel called acetyl-CoA, which the mitochondria can use as an energy source instead of pyruvate. | |
The cardiologists speculate that the findings could also inspire the development of new drugs for heart failure that work by boosting the breakdown of fatty acids in heart muscle cells. | |
Cardiovascular risk | The American Heart Association's dietary guidelines for cardiovascular disease contradict the high-fat/low-carb ketogenic diet. |
Studies looking at CVD risks of high-fat, low-carbohydrate diets have shown mixed results. | |
A meta-analysis of 11 randomized controlled trials found that ketogenic diets promoted greater weight loss than low-fat diets, but they also increased low-density lipoprotein cholesterol (LDL-C). | |
A meta-analysis by Nordmann and colleagues comparing low-fat and low-carbohydrate diets found that ketogenic diets improved triglyceride and high-density lipoprotein cholesterol values but worsened LDL-C. | |
These contradictory findings are probably due to differences between the types of ketogenic diets used and how each study was modeled. | |
Long-term effects | Overall, assessment of the ketogenic diet's long-term effects on cardiac function in the setting of HF are limited. |
In fact, most studies to date have evaluated only short-term effects of a ketogenic diet in patients without HF or other cardiovascular risk factors. |
What You'll Learn
- The keto diet may help with weight loss and improving heart health
- The keto diet may reduce insulin levels, which can help with weight loss and improving cholesterol
- The keto diet may help with fasting, which can have health benefits
- The keto diet may increase autophagy, which can help with cellular housekeeping
- The keto diet may be enjoyable, which can help with long-term adherence
The keto diet may help with weight loss and improving heart health
The keto diet is a low-carbohydrate, fat-rich eating plan that has been used for centuries to treat specific medical conditions. In the 19th century, it was used to help control diabetes, and in 1920, it was introduced as an effective treatment for epilepsy. Today, it is gaining popularity as a potential weight-loss strategy and has been tested and used in closely monitored settings for cancer, diabetes, polycystic ovary syndrome, and Alzheimer's disease.
Additionally, the keto diet can lead to a reduction in insulin levels, which is essential for health and weight loss. Insulin promotes fat storage, increases inflammation, and can even fuel the growth of cancer cells. A keto diet improves the body's sensitivity to insulin, reduces the amount of insulin secreted, and allows the body to use fat stores for energy.
The keto diet has also been shown to improve cholesterol levels. While it may increase LDL cholesterol, it also increases HDL cholesterol, which is associated with a lower risk of heart disease. The total cholesterol to HDL ratio, triglyceride to HDL ratio, lipoprotein size and density, insulin sensitivity, and other metabolic measures are more powerful predictors of cardiovascular health than just LDL.
Furthermore, the keto diet can lead to increased energy levels and improved exercise performance. With more available fat for fuel, the body has a constant and unwavering supply of energy, which can enhance physical endurance.
However, it is important to note that the keto diet may not be suitable for everyone. It is always recommended to consult with a healthcare professional before starting any new diet, especially if you have existing health conditions. Additionally, the keto diet can be challenging to maintain in the long term and may not be sustainable for everyone.
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The keto diet may reduce insulin levels, which can help with weight loss and improving cholesterol
The keto diet is a low-carb, high-fat diet that changes metabolism so that energy comes from fat instead of sugar. This diet has been shown to reduce weight and improve cardiovascular health.
Insulin is a hormone that helps the body control levels of blood sugar, or glucose. Insulin resistance is a condition where organs and tissues lose their ability to respond to insulin. This can lead to hyperglycemia, which is a hallmark of diabetes.
The keto diet improves insulin sensitivity, reduces the amount of insulin secreted, and allows the body to use fat stores as energy. This diet can also improve cholesterol levels.
A high-fat, low-carb diet reversed heart failure in a mouse model of the condition. The ketogenic diet has been growing in popularity in recent years, with research suggesting that it has a range of possible health benefits. These include supporting weight loss, improving heart health, and preventing seizures in some types of epilepsy.
The new research indicates that a ketogenic diet promotes the breakdown of fatty acids in heart muscle cells. This process produces an alternative fuel called acetyl-CoA, which the mitochondria can use as an energy source instead of pyruvate.
The findings from this study suggest that consumption of higher fat and lower carbohydrate diets may be a nutritional therapeutic intervention to treat heart failure.
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The keto diet may help with fasting, which can have health benefits
The keto diet and fasting are two of the most popular health trends today. While both have solid research backing their purported benefits, many wonder if it is safe and effective to combine the two.
Ketogenic Diet
The ketogenic (keto) diet is a high-fat, very low-carb way of eating. Carbs are typically reduced to 20 to 50 grams per day, which forces your body to rely on fats instead of glucose for its main energy source. In the metabolic process known as ketosis, your body breaks down fats to form substances called ketones that serve as an alternate fuel source.
The keto diet has been used for nearly a century to treat epilepsy and also demonstrates promise for other neurological disorders. For instance, the keto diet may improve mental symptoms in people with Alzheimer’s disease. What’s more, it may reduce blood sugar, improve insulin resistance and lower heart disease risk factors like triglyceride levels.
Intermittent Fasting
Intermittent fasting is an eating method that cycles between calorie restriction — or fasting — and normal food consumption during a specific time period. There are many different types of intermittent fasting routines, including the 5:2 method, the Warrior Diet and alternate-day fasting. Perhaps the most popular kind of intermittent fasting is the 16/8 method, which involves eating during an eight-hour timeframe before fasting for 16.
Intermittent fasting is mainly used as a weight loss technique. However, studies found that it may benefit health in many other ways. For example, intermittent fasting has been shown to reduce inflammation and improve brain function and blood sugar control.
Combining the Two
Combining the ketogenic diet with intermittent fasting is likely safe for most people. However, pregnant or breastfeeding women and those with a history of disordered eating should avoid intermittent fasting. People with certain health conditions, such as diabetes or heart disease, should consult with a doctor before trying intermittent fasting on the keto diet.
Combining the two diets gained popularity when intermittent fasting expert Jason Fung, MD, author of The Obesity Code, recommended using keto as a foundation with fasting. Celebrities including Halle Berry and Jennifer Aniston have been reported to use both diets together.
Benefits of Combining the Two
Combining the diet and the fast may help you burn more fat than the diet alone. Because intermittent fasting boosts metabolism by promoting thermogenesis, or heat production, your body may start utilizing stubborn fat stores. Several studies reveal that intermittent fasting can powerfully and safely drop excess body fat.
In an eight-week study in 34 resistance-trained men, those who practiced the 16/8 method of intermittent fasting lost nearly 14% more body fat than those following a normal eating pattern. Similarly, a review of 28 studies noted that people who used intermittent fasting lost an average of 7.3 pounds (3.3 kg) more fat mass than those following very low-calorie diets.
Plus, intermittent fasting may preserve muscle mass during weight loss and improve energy levels, which may be helpful for keto dieters looking to improve athletic performance and drop body fat. Additionally, studies underscore that intermittent fasting can reduce hunger and promote feelings of fullness, which may aid weight loss.
Potential Risks
As for long-term risks, “people with seizure disorders (what keto was developed to treat) have been on the ketogenic diet for decades and demonstrate excellent health,” says Dominic D’Agostino, PhD, associate professor at the University of South Florida in Tampa and founder of KetoNutrition.org. Though, like any diet, it all depends on what foods you’re eating. A keto diet rich in bacon and butter is different from one rich in avocado and olive oil, and poorly planned keto can lead to nutritional deficiencies. Because adding IF may make you cut calories too drastically, you may also lose too much weight or lean mass (muscle) if you take the restriction to the extreme.
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The keto diet may increase autophagy, which can help with cellular housekeeping
The keto diet, a high-fat, low-carb approach, can trigger autophagy by changing the way the body burns energy. Instead of burning carbohydrates or sugar for energy, the body burns fat, which can induce autophagy. This is because autophagy occurs when the body's cells are deprived of nutrients or stressed, and the keto diet mimics the effects of fasting, sending the cells into survival mode.
Autophagy is like the body's housekeeping process, where cells break down and recycle their contents. During autophagy, cells disassemble their junk parts and repurpose the salvageable bits into new, usable cell parts. This process is facilitated by autophagy-related proteins (ATGs) and structures called autophagosomes, which carry the junk cell pieces to a lysosome for digestion.
By inducing autophagy through the keto diet, individuals may experience a range of benefits, including improved cellular repair, protection from neurodegenerative diseases, enhanced immunity, detoxification, and improved metabolic efficiency. Additionally, autophagy promotes healthy aging by preventing the buildup of harmful elements, reducing the risk of heart disease, cancer, and metabolic conditions.
While the keto diet may increase autophagy, it is important to note that autophagy is a complex process that is not yet fully understood. More research is needed to determine the ideal timing and methods to trigger autophagy in humans, as most studies have been conducted on animals. Furthermore, inducing autophagy through drastic dietary changes or fasting may not be safe for everyone, especially those with certain health conditions. Consulting a healthcare provider before making significant dietary changes is always recommended.
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The keto diet may be enjoyable, which can help with long-term adherence
The keto diet is a low-carb, high-fat diet that has been gaining popularity in recent years. It involves drastically reducing carbohydrate intake and replacing it with healthy fats, which can promote weight loss and improve overall health. While the diet can be restrictive, there are still many delicious and nutritious food options to choose from, making it an enjoyable and sustainable way of eating for many people.
Variety of Tasty Food Options
Keto-friendly foods include a variety of delicious options such as meat, fish, seafood, eggs, cheese, vegetables, nuts, and berries. You can enjoy tasty meals like chicken salad with olive oil and feta cheese, salmon with asparagus, and cheese-shell tacos. There are also keto-friendly snacks like nuts, hard-boiled eggs, and guacamole. The diet even allows for the occasional glass of wine!
Weight Loss Without Hunger
The keto diet is an effective way to lose weight, and one of the best things about it is that you don't have to count calories or feel hungry all the time. The high-fat content of the diet helps you feel fuller for longer, reducing cravings and making it easier to stick to the plan.
Improved Health and Energy Levels
The keto diet has been shown to improve various health markers, including blood sugar, insulin levels, and HDL ("good") cholesterol. Many people also experience increased energy levels and better mental focus while on the keto diet. These health benefits can further motivate individuals to stick with the diet long-term.
Flexibility and Convenience
The keto diet can be adapted to suit different preferences and lifestyles. There are several versions of the diet, such as the standard ketogenic diet (SKD) and the cyclical ketogenic diet (CKD), allowing individuals to choose the approach that works best for them. Additionally, the diet doesn't require strict meal planning or complex recipes, making it convenient for busy individuals.
Community and Support
With the growing popularity of the keto diet, there is now a large community of people following the diet and sharing their experiences, recipes, and tips online. This sense of community and support can help individuals stay motivated and committed to the diet long-term.
In conclusion, the keto diet may be enjoyable for many people due to the variety of tasty food options, effective weight loss without hunger, improved health and energy levels, flexibility, and the sense of community and support. These factors can all contribute to long-term adherence and help individuals reap the benefits of the keto diet.
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Frequently asked questions
The ketogenic diet has been shown to improve blood sugar control for patients with type 2 diabetes, at least in the short term. It has also been shown to reduce seizures in children with epilepsy. However, there is no long-term research analyzing its effects on diabetes and high cholesterol.
The ketogenic diet is a high-fat, low-carbohydrate diet that causes the body to release ketones into the bloodstream. It typically includes plenty of meats, eggs, processed meats, sausages, cheeses, fish, nuts, butter, oils, seeds, and fibrous vegetables.
The ketogenic diet is associated with an increase in "bad" LDL cholesterol, which is linked to heart disease. It may also cause nutrient deficiency, liver problems, kidney problems, constipation, fuzzy thinking, and mood swings.