
Methamphetamine, commonly known as meth, has been used as a prescription drug to treat attention deficit hyperactivity disorder (ADHD) and exogenous obesity. In the 1950s and 1960s, a popular diet pill in America called Obetrol contained a combination of amphetamine mixed salts and methamphetamine. While methamphetamine can be used to treat obesity, it is highly addictive and can cause serious side effects, including sudden death, heart attack, and stroke. Due to its addictive nature and potential for abuse, the FDA withdrew approval for Obetrol in 1973, and the drug is now considered illicit.
Are diet pills meth?
| Characteristics | Values |
|---|---|
| History | Methamphetamine was first used as a prescription drug by the German Armed Forces during World War II. In the 1950s and 1960s, it was a popular diet pill in America under the brand name Obetrol. |
| Regulation | In 1970, the FDA required new drug applications for previously approved amphetamine products and combinations. In 1973, the FDA withdrew approval for Obetrol due to insufficient research and potential health risks. |
| Side Effects | Methamphetamine is highly addictive and dangerous. It can cause sudden death, heart attack, or stroke, especially in individuals with heart defects or serious heart problems. Other side effects include agitation, hallucinations, fever, sweating, confusion, and nausea. |
| Treatment | Addiction to methamphetamine is challenging but can be overcome with professional help and proven programs. |
| Current Usage | Methamphetamine is currently used to treat ADHD in children and as a short-term weight loss aid for obese individuals under medical supervision. |
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What You'll Learn

History of methamphetamine as a prescription drug
Methamphetamine was first synthesised in 1893 and went on to be used for a wide array of medical treatments. During the same time period, a German chemist also created amphetamine, which was originally named phenylisopropylamine. In 1919, the first crystallised methamphetamine was created in a Japanese lab.
During World War II, the Japanese, German, British, and U.S. militaries supplied soldiers with methamphetamine tablets to help them stay alert and be willing to take risks. German pharmaceutical company Temmler marketed methamphetamine tablets as a non-prescription drug under the brand name Pervitin.
In the 1950s, methamphetamine was legally manufactured in the United States. People used it for weight control and to boost energy. Truck drivers would use it to stay awake for long shifts, and athletes would use it to increase their stamina. Obetrol, a popular diet pill in America in the 1950s and 1960s, was a combination of several amphetamine salts used to treat exogenous obesity. The original formulation of amphetamine mixed salts and methamphetamine was approved by the U.S. Food and Drug Administration (FDA) on January 19, 1960.
In 1970, the U.S. Drug Abuse Regulation and Control Act was passed, severely restricting the legal production of injectable methamphetamine and causing its use to decrease. Soon, prescriptions dropped severely, and illicit market production ramped up. In September 1973, the FDA withdrew approval for Obetrol, citing vague and incomplete research.
In 2004, an estimated 12 million people in the United States over the age of twelve had tried meth at least once. The Combat Methamphetamine Epidemic Act of 2005 restricted the availability of pseudoephedrine, a common ingredient in meth production, by requiring pharmacies and retail stores to move products containing pseudoephedrine behind the counter and limit the quantity customers could purchase.
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Obetrol: a diet pill with methamphetamine
Obetrol was a popular diet pill in America in the 1950s and 1960s. The drug combined several amphetamine salts and was indicated for the treatment of exogenous obesity. The original formulation of amphetamine mixed salts and methamphetamine was approved by the U.S. Food and Drug Administration (FDA) on January 19, 1960, under the name Obetrol.
Obetrol was first manufactured by Obetrol Pharmaceuticals in Brooklyn, New York. The company later became a division of Rexar Pharmacal Corporation, which was also headquartered in Brooklyn. From 1965 to 1973, Obetrol was marketed in 10 mg and 20 mg strengths through Obetrol Pharmaceuticals, a division of the American pharmaceutical company Rexar. When sold directly to physicians, Obetrol used the brand name Oby-Rex.
In 1970, the FDA issued an order requiring new drug applications for previously approved amphetamine products. The FDA was critical of combinations of amphetamines and non-amphetamines, and required the ingredients to be effective and safe individually and in combination. In September 1973, the FDA withdrew approval for Obetrol, citing vague and incomplete research.
In response, Rexar reformulated Obetrol to exclude methamphetamine salts and continued to sell this new formulation under the same Obetrol brand name. There is no drug commercially marketed as Obetrol today, nor has there been since Richwood acquired Rexar Pharmacal.
The ready availability of methamphetamine-based medications in the 1960s led to their use and abuse as recreational drugs. Methamphetamine is a highly addictive and dangerous drug that has been linked to sudden death, heart attack, and stroke in adults, especially those with heart defects or serious heart problems. It is important to note that methamphetamine addiction can be overcome with professional help and a proven program.
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The addictive nature of methamphetamine
Methamphetamine is a highly addictive central nervous system stimulant. Its unique properties make it extremely addictive. It can enter the brain quickly and produce an intense "rush" or euphoria that ends swiftly, making the drug highly reinforcing and leading to repeated use. The drug is becoming more widely available and accessible, with methamphetamine-based medications in the 1960s leading to their use and abuse as recreational drugs.
The repeated use of methamphetamine can lead to methamphetamine use disorder, with symptoms such as anxiety, confusion, insomnia, mood disturbances, and psychosis, including hallucinations and delusions. Heavy drinking and stress increase the likelihood of a recurrence of psychosis symptoms. Long-term use has also been associated with decreased cognitive function, including difficulties with verbal learning and slower reaction times.
Methamphetamine use is also linked to a range of severe health issues, including cardiovascular and renal dysfunction, infectious disease transmission, and overdose. The overlap of methamphetamine use with mental illness suggests an important role for mental health providers in coordinating care with addiction specialists. Treatment of co-occurring mental and substance use disorders has been recognised as a gap in the system of care.
In summary, methamphetamine is a highly addictive drug that can lead to severe health problems and disorders. Its unique properties, including its ability to induce a rapid and intense high, make it highly reinforcing and contribute to its addictive nature. The availability and accessibility of the drug have increased, contributing to its widespread use and associated harms.
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Methamphetamine as a treatment for ADHD
Methamphetamine has been used to treat Attention Deficit Hyperactivity Disorder (ADHD) in both adults and children over the age of six. It is an integral part of a total treatment program for ADHD, which includes other remedial measures such as psychological, educational, and social interventions. The medication is designed to increase attention and decrease restlessness in patients who are overactive, have difficulty concentrating, or are easily distracted and impulsive. The typical starting dosage for adults and children aged six and above is 5 milligrams, taken one or two times per day, and should not exceed 25 milligrams per day. It is important to note that the dose may be adjusted by a doctor as needed.
The history of methamphetamine is quite interesting. It was first used by the German Armed Forces during World War II to enhance the performance of their troops. Later, in the 1950s and 1960s, it was a popular ingredient in American diet pills under the brand name Obetrol. Obetrol was a combination of several amphetamine salts indicated for the treatment of obesity. In 1960, the U.S. Food and Drug Administration (FDA) approved the drug.
However, in 1970, the FDA began to critically review combination drugs containing amphetamines and required that each ingredient be proven effective and safe individually and in combination. As a result, in 1973, the FDA withdrew its approval of Obetrol, citing vague and incomplete research. Despite this, the availability of methamphetamine-based medications in the 1960s led to their recreational use and abuse.
Methamphetamine is a highly addictive substance, and its use as a prescription drug is carefully monitored. It is only available with a doctor's prescription, and patients are advised to take it exactly as directed to avoid the risk of dependency. It is also important to note that methamphetamine may cause unwanted side effects, and patients are advised to consult their doctor if any adverse reactions occur.
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Side effects of methamphetamine
Methamphetamine, also known as meth, chalk, ice, crystal, or crank, is a highly addictive stimulant that can be smoked, snorted, injected, or administered orally or rectally. It is a synthetic drug with a high potential for abuse and addiction. The short-term effects of methamphetamine use include increased alertness, talkativeness, sociability, confidence, energy, and sex drive, as well as decreased appetite. However, it can also cause serious negative health effects, including paranoia, anxiety, rapid heart rate, irregular heartbeat, stroke, or even death.
The long-term use of methamphetamine may lead to insomnia, memory loss, development of a substance use disorder, and other health problems. It can also cause severe damage to the central nervous system. Methamphetamine affects many of the body's organs and systems, and persistent use is the largest risk factor for acquiring HIV in sexual minorities who have sex with men. The sharing of injection equipment among people who use methamphetamine may also transmit hepatitis B and C.
Methamphetamine use can also lead to changes in sexual behavior, such as having more sexual partners and less use of protective measures, further increasing the chances of HIV and viral hepatitis transmission. Additionally, methamphetamine use can make HIV treatment less effective. The repeated use of methamphetamine increases the risk of developing a methamphetamine use disorder, and symptoms of psychosis, such as hallucinations and delusions, may occur even when the user is not intoxicated.
The powerful stimulant effects of methamphetamine can provide users with increased energy and a sense of happiness, leading to a quick onset of addiction. The drug's intense effects and low cost make it highly addictive, and the negative consequences can be devastating. While methamphetamine addiction was once considered incurable, recent studies and successful rehabilitations have proven that it can be overcome with professional help and proven programs.
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Frequently asked questions
Diet pills are medications that aim to help with weight loss. They often contain stimulants and are usually taken orally.
Methamphetamine, also known as meth, is a highly addictive and dangerous central nervous system stimulant. It was once used as a prescription drug to treat ADHD and obesity but is now primarily abused as an illicit substance.
Some diet pills in the past contained methamphetamine. Obetrol, a popular diet pill in America during the 1950s and 1960s, was a combination of amphetamine and methamphetamine salts. However, due to concerns about the safety of these drugs, the FDA withdrew approval for Obetrol in 1973. Today, methamphetamine is not approved for weight loss and is not an ingredient in any commercially marketed diet pill.
Methamphetamine is a highly addictive and dangerous drug. It can cause serious side effects, including sudden death, heart attack, or stroke, especially in individuals with heart defects or serious heart problems. It can also lead to agitation, hallucinations, fever, confusion, and difficulty sleeping, among other symptoms.





























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