Yohimbe is a supplement derived from the bark of the Pausinystalia yohimbe tree, native to western and central Africa. It is commonly used to treat erectile dysfunction and promote fat loss. Yohimbine, the active ingredient in yohimbe, is believed to work by blocking alpha-2 adrenergic receptors, which play a role in inhibiting erections. This supplement has also gained popularity among bodybuilders and dieters for its potential fat-burning properties.
There is some evidence to suggest that yohimbe can aid weight loss by blocking alpha receptors, which increases the effect of norepinephrine in inducing a state of ketogenesis, where ketones are produced from fats in the absence of carbohydrates. This leads to an increased breakdown of fat and subsequent weight loss. However, the scientific research on yohimbe's fat-burning effects is limited and inconclusive, with some studies finding no significant impact on body composition or lipolysis.
It is important to note that yohimbe carries certain health risks and is not suitable for everyone. It can cause side effects such as increased heart rate, anxiety, nausea, abdominal pain, and dizziness. Additionally, there have been reports of inaccurate labelling on yohimbe products, which could lead to harmful side effects if consumed in incorrect dosages. As with any supplement, it is advisable to consult a doctor or healthcare professional before use.
Characteristics | Values |
---|---|
What is Yohimbe? | A supplement made from the bark of the Yohimbe tree, native to Africa. |
Yohimbe's active ingredient | Yohimbine, an alkaloid with a bitter taste. |
Yohimbine's function | Blocks alpha-2 adrenergic receptors, which inhibit erections, thus helping with erectile dysfunction. |
Yohimbine's effect on the body | Increased heart rate, improved blood circulation, and more energy. |
Yohimbine's effect on fat loss | Yohimbine blocks alpha receptors, allowing the body's catecholamines to bind to beta receptors, which burn fat. |
Yohimbine's effect on appetite | Appetite suppression, as seen in animal studies. |
Yohimbine's effect on ketosis | Yohimbine may be more effective in a fasted state, but even small amounts of protein or fat can blunt its effects. |
Yohimbine's side effects | Nausea, abdominal pain, dizziness, nervousness, increased blood pressure, and anxiety. |
Yohimbine's safety | Not suitable for people with a history of heart disease, high or low blood pressure, or mental health conditions. Not recommended for pregnant people or children under 18. |
What You'll Learn
Yohimbe and Yohimbine
Yohimbe is a supplement derived from the bark of the Pausinystalia yohimbe, an evergreen tree native to western and central Africa. It has been used in West African traditional medicine to improve sexual performance and is now also marketed as a dietary supplement for weight loss. The active ingredient in yohimbe is yohimbine, an alkaloid that has been shown to increase sexual activity and promote fat loss.
Yohimbine works by blocking alpha-2 adrenergic receptors, which are responsible for inhibiting erections. By blocking these receptors, yohimbine helps to alleviate erectile dysfunction. Yohimbine is available as a prescription drug called yohimbine hydrochloride for treating erectile dysfunction. It can also be purchased over the counter as a dietary supplement in the form of yohimbe bark extract or yohimbine hydrochloride.
In addition to its effects on sexual performance, yohimbine has been found to increase energy levels and improve blood circulation, making it a popular ingredient in pre-workout supplements. It also has fat-burning properties, as it blocks alpha subunits in fat cells, allowing for more efficient fat burning. Studies have shown that yohimbine supplementation can lead to increased weight loss and reduced body fat percentage in humans. However, the data is limited and inconclusive, with some studies finding no significant effect on body composition or lipolysis.
It is important to note that yohimbe and yohimbine carry certain health risks and may not be suitable for everyone. There have been reports of inaccurate labelling and potentially serious side effects, including increased heart rate, nausea, abdominal pain, dizziness, and nervousness. It can also increase blood pressure and induce anxiety-like symptoms. As such, it is recommended to consult a doctor before taking yohimbe or yohimbine and to purchase supplements from reputable companies that clearly label the yohimbine content.
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Ketosis and Yohimbe
Yohimbe is a supplement derived from the bark of the Pausinystalia yohimbe tree, which is native to western and central Africa. It has been used in West African traditional medicine to improve sexual performance and is now also marketed as a weight-loss aid.
Yohimbine is the active ingredient in yohimbe bark. It works by blocking alpha-2 adrenergic receptors, which are found in the body's fat cells. When these receptors are blocked, fat loss becomes easier. Beta subunits, another type of adrenergic receptor, increase fat loss by raising the levels of the enzyme adenyl cyclase, which is involved in energy metabolism and cell signalling. On the other hand, alpha subunits suppress fat loss by doing the opposite. Yohimbe is an alpha-adrenergic antagonist, meaning it decreases the activity of alpha subunits and allows beta subunits and adenyl cyclase to burn fat.
Ketosis is a state in which the body produces ketone bodies by breaking down fats. This happens when the body is in a ketogenic state, or very low-carbohydrate diet, and starts making ketones by breaking down fats to be used as an energy source by the brain.
Blocking alpha receptors can increase the effect of norepinephrine in inducing a state of ketogenesis. As yohimbe burns fat by blocking alpha subunits, it can be assumed that it also supports ketogenesis. This is because yohimbine, the active ingredient in yohimbe, increases the presence of ketone bodies by breaking down fats.
Yohimbe and Weight Loss
There is some evidence that yohimbe can cause weight loss in humans. In one study, obese individuals were given either a placebo or 5mg of yohimbine four times a day for three weeks, in addition to being kept on a low-calorie diet. The weight loss in the yohimbine-treated group was 3.55kg, while the result in the placebo group was 2.21kg.
Another study found that yohimbine supplementation caused a 9.3% decrease in body fat in the treatment group, compared to a 7.1% decrease in the placebo group.
Precautions
It is important to note that yohimbe can have adverse side effects, including an increased heart rate, and should be taken with caution. It is also recommended that it be taken in a fasted state, as ingestion of food reduces its fat-burning effects.
In addition, yohimbe has been found to reinforce food-seeking or addictive behaviour, which can make it more difficult to stick to a diet. Some studies have also found that yohimbine supplementation has no effect on fat composition and does not cause fat loss.
As with any supplement, it is best to consult a doctor about the side effects, interactions with other drugs, and the correct dosage.
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Yohimbe's effect on stubborn fat
Yohimbe is a supplement derived from the bark of the Pausinystalia yohimbe tree, native to western and central Africa. It has been used in West African traditional medicine for centuries and is now marketed as a dietary supplement to aid weight loss and treat erectile dysfunction.
Yohimbine, the active ingredient in yohimbe bark, is believed to aid fat loss by blocking alpha-2 adrenergic receptors in the body's fat cells. When these receptors are blocked, catecholamines (hormones produced by the adrenal glands) are better able to bind to beta receptors, which facilitates fat burning.
Increased Heart Rate:
Yohimbe can increase heart rate, particularly when combined with other stimulating ingredients. This helps the body burn more calories at rest and during activity, leading to potential weight loss.
Appetite Suppression:
Yohimbe has been shown to suppress appetite in animal studies, and this effect may also occur in humans. This can help individuals maintain a calorie deficit, which is crucial for burning body fat and losing weight.
Improved Blood Circulation:
Yohimbe influences the sympathetic nervous system, which is responsible for the body's "fight or flight" response. This improves blood circulation, delivering more oxygen and nutrients to the muscles, enhancing workout performance and recovery.
Increased Energy:
By stimulating the sympathetic nervous system, yohimbe can provide an energy boost, enabling individuals to push themselves harder during workouts and potentially burn more fat.
Reduced Fatigue:
The increased energy provided by yohimbe can help reduce fatigue, allowing individuals to train for longer durations without feeling as tired, which may contribute to faster fat loss.
Increased Water Loss:
Yohimbe can aid in shedding excess water weight, making it a popular choice for bodybuilders and individuals seeking to quickly reduce their body weight.
Reduced Muscle Loss:
Yohimbe appears to speed up fat loss without causing a loss of muscle mass, which is beneficial for maintaining a desirable physique and a healthy metabolism.
Dosage and Timing:
The optimal dosage of yohimbe is generally considered to be around 0.2 mg per kilogram of body weight. It is recommended to take yohimbe in a fasted state, as elevated insulin levels may negate its fat-loss benefits. Consuming yohimbe first thing in the morning or before a workout can be an effective strategy.
Precautions:
While yohimbe offers potential benefits for fat loss, it also carries certain risks. It can cause adverse side effects, including increased heart rate, anxiety, nausea, abdominal pain, and nervousness. It may also negatively impact heart function and reinforce food addiction. Therefore, it is essential to consult a healthcare professional before taking yohimbe and to purchase supplements from reputable companies that provide accurate labelling and testing for quality and safety.
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Yohimbe's side effects
Yohimbine, the active ingredient in yohimbe, has been associated with several side effects, ranging from mild to severe. Here is a detailed overview:
Cardiovascular Side Effects
Yohimbine can cause an increase in heart rate and blood pressure, leading to cardiovascular issues such as tachycardia (rapid heart rate) and elevated blood pressure. This is particularly concerning for individuals with pre-existing heart disease, high or low blood pressure, or other cardiovascular conditions.
Nervous System Side Effects
The supplement can also affect the nervous system, causing dizziness, excitation, increased motor activity, tremors, and nervousness. It can trigger 'fight or flight' responses, leading to increased heart rate and blood pressure. For individuals with anxiety or panic disorders, yohimbine may worsen symptoms and cause restlessness.
Gastrointestinal Issues
There have been reports of gastrointestinal side effects such as nausea and vomiting, especially after parenteral administration of yohimbine.
Psychiatric Effects
Yohimbine may cause psychiatric side effects, including irritability, anxiety, and confusion or unusual behaviour. It can also worsen panic attacks and trigger hallucinations in some cases.
Dermatologic Reactions
Oral administration of yohimbine has been associated with skin flushing.
Allergic Reactions
In some cases, individuals may experience allergic reactions to yohimbine, including difficulty breathing, swelling of the lips, tongue, or face, and hives.
Other Side Effects
Yohimbine has also been linked to increased sweating, red and bloodshot eyes, insomnia, and temporary paralysis. It can also cause prolonged or painful erections (priapism) and interact with other medications, particularly antidepressants.
It is important to note that yohimbine is not suitable for everyone, especially pregnant individuals and children under 18. Always consult a healthcare professional before taking yohimbine or making any significant dietary changes, such as following a keto diet.
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Yohimbe's benefits
Yohimbe is a supplement made from the bark of the Pausinystalia yohimbe, an evergreen tree native to western and central Africa. It has been used in West African traditional medicine for centuries to improve sexual performance.
Yohimbine is the active ingredient in yohimbe bark and is available as a prescription drug for treating erectile dysfunction. However, yohimbe supplements are also readily available over the counter.
Improved Blood Circulation
Yohimbe influences the body's sympathetic nervous system, which is responsible for triggering the "fight or flight" response. This results in improved blood circulation, delivering more blood, oxygen, and nutrients to the muscles. This can enhance workout performance and aid in post-workout recovery.
Increased Energy
By stimulating the sympathetic nervous system, yohimbe can make you feel more energised, helping you to lift heavier weights and push yourself harder during workouts.
Improved Fat Loss
Yohimbe is believed to aid in fat loss by acting as an alpha-2 receptor antagonist. It blocks the alpha-2 receptors found in fat cells, allowing catecholamines (hormones produced during the fight-or-flight response) to bind to beta receptors instead. This facilitates fat mobilisation and burning.
Additionally, yohimbe can increase heart rate, further boosting calorie burning. It also suppresses appetite, making it easier to maintain a calorie deficit, which is crucial for weight loss.
Reduced Fatigue
The increase in energy provided by yohimbe enables you to work out for longer periods without feeling fatigued, allowing you to burn more calories and accelerate fat loss.
Increased Water Loss
Yohimbe can be beneficial when quick weight loss is needed, as it helps eliminate excess water weight, making you appear leaner and more "stage-ready," which is advantageous for bodybuilders and those preparing for photoshoots or events.
Reduced Muscle Loss
Yohimbe appears to speed up fat loss without causing a loss of muscle mass, helping to maintain an ideal physique and a faster metabolism.
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Frequently asked questions
Taking Yohimbe supplements carries certain health risks and it is not suitable for everyone. It is advised that pregnant people, children under 18, and people with a history of heart disease, high or low blood pressure, and mental health conditions should not take Yohimbe.
Yohimbe is a supplement that can help treat erectile dysfunction and promote fat loss. It is also said to improve blood circulation, increase energy, and suppress appetite.
Yohimbe is a naturally occurring ingredient found in many pre-workout supplements. It comes from the bark of the Yohimbe tree, an evergreen tree native to parts of central and western Africa.
Yohimbe acts as an Alpha-2 receptor antagonist, blocking the Alpha-2 receptors found in the body's fat cells. This makes it easier for fat cells to mobilize and be burned for energy. Yohimbe also increases heart rate, helping the body burn more calories at work and at rest.
It is recommended to take Yohimbe in a fasted state, between meals, and before a workout. The optimal dosage is around 0.2mg per kilogram of body weight. For example, this would be approximately 14mg for a 150-pound person.