7-keto-DHEA is a supplement that may increase your metabolism and lead to weight loss. It is a naturally occurring metabolite of the steroid hormone dehydroepiandrosterone (DHEA) and is produced in the adrenal glands. Unlike DHEA, 7-keto-DHEA is not converted to hormones like androgen and estrogen. Instead, it has thermogenic properties, increasing the body's metabolic rate and converting energy to heat instead of storing it as fat.
While there is limited research on the effectiveness of 7-keto-DHEA for weight loss, a few studies have shown promising results. One eight-week study found that participants who took 200 mg of 7-keto-DHEA daily and followed a calorie-restricted diet and exercise regimen lost an average of 6.3 pounds, compared to 2.1 pounds in the placebo group. Another study showed a weight reduction of 2.2% in participants taking 7-keto-DHEA.
However, it's important to note that the research on 7-keto-DHEA is limited, and more studies are needed to determine its effectiveness and safety for weight loss. Additionally, it is recommended to consult with a healthcare professional before taking any supplements, especially if you have any health concerns or are pregnant or breastfeeding.
Characteristics | Values |
---|---|
What is it? | A supplement that may increase your metabolism and lead to weight loss |
How does it work? | It speeds up the body's metabolism and converts more energy to heat instead of storing it as fat |
Is it safe? | It is possibly safe when used for up to 8 weeks and is well tolerated when used short-term |
Dosage | The recommended dosage is 100-200 mg per day |
Weight loss | In an eight-week study, participants lost 6.3 pounds (2.88 kg) |
Other effects | May influence sex hormones, cholesterol, and thyroid function |
Other names | 3-beta)-3-hydroxyandrost-5-ene-7,17-dione; (3S,8R; 7-Keto |
What You'll Learn
- keto-DHEA is a supplement that may increase your metabolism and lead to weight loss
- keto-DHEA is safe for short-term use and is well-tolerated
- keto-DHEA is formed from dehydroepiandrosterone (DHEA) in the body
- keto-DHEA is not converted to hormones like androgen and estrogen
- keto-DHEA is banned by WADA and may influence male hormones when used as a gel
7-keto-DHEA is a supplement that may increase your metabolism and lead to weight loss
The benefits of 7-keto-DHEA supplementation are not definitively established. While it is marketed as a more effective way to induce heat production (thermogenesis) for weight loss compared to DHEA, these claimed benefits are not supported by solid evidence. The current evidence is mixed and limited by factors such as small sample sizes, short study durations, and a lack of diversity in the study populations.
However, some studies have shown promising results for 7-keto-DHEA as a weight loss aid. In one eight-week study, participants who received 200 mg per day of 7-Keto lost 6.3 pounds (2.88 kg), compared to a 2.1-pound (0.97 kg) weight loss in the placebo group. Another study found that a supplement containing 7-keto-DHEA combined with seven other ingredients resulted in a weight loss of 4.8 pounds (2.2 kg), compared to 1.6 pounds (0.72 kg) in the placebo group.
It is important to note that 7-keto-DHEA supplements have been suggested to trigger positive tests for performance-enhancing drugs. As a result, the World Anti-Doping Agency (WADA) has listed 7-keto-DHEA as a prohibited anabolic agent.
Overall, while 7-keto-DHEA may increase metabolism and lead to weight loss, more research is needed to definitively establish its benefits and safety, particularly with long-term use.
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7-keto-DHEA is safe for short-term use and is well-tolerated
7-keto-DHEA is a supplement that may increase your metabolism and lead to weight loss. It is formed from dehydroepiandrosterone (DHEA), a hormone produced by the adrenal glands. Unlike DHEA, 7-keto-DHEA is not converted to hormones like androgen and estrogen. Instead, it may increase the body's metabolism and convert more energy to heat, thus promoting weight loss.
When taken orally, 7-keto-DHEA is possibly safe for short-term use of up to 8 weeks and is well-tolerated. However, there is limited research on its long-term safety and effectiveness. It is important to note that natural products are not always safe, and dosages can be important. It is recommended to follow relevant directions on product labels and consult a healthcare professional before using any supplement.
In terms of weight loss, the results from studies have been mixed. Some studies have shown significant weight loss, while others have found no significant differences in weight loss between the treatment and placebo groups. The duration of these studies has varied, with some being as short as one week and others lasting up to eight weeks. It is worth noting that the World Anti-Doping Association (WADA) has listed 7-keto-DHEA as a prohibited anabolic agent due to its potential performance-enhancing effects.
Overall, 7-keto-DHEA is considered safe for short-term use and is well-tolerated, but more research is needed to determine its long-term safety and effectiveness for weight loss.
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7-keto-DHEA is formed from dehydroepiandrosterone (DHEA) in the body
7-keto-DHEA is a steroid prohormone produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). It is not converted to hormones like androgen and estrogen, unlike DHEA. This means that 7-keto-DHEA does not increase the amount of these hormones in the blood when taken as an oral supplement.
The body naturally produces DHEA, a hormone that comes from the adrenal glands located on top of each of the kidneys. DHEA is one of the most abundant circulating steroid hormones in the body and functions as a precursor for male and female sex hormones, including testosterone and estrogen.
The synthesis of 7-keto-DHEA begins with an irreversible hydroxylation of DHEA in the position C7 by cytochrome P450 7B1 (CYP7B1). This forms 7-alpha-hydroxy-dehydroepiandrosterone (7-alpha-OH-DHEA). 7-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD 1) then catalyzes the interconversion of 7-beta-hydroxy-dehydroepiandrosterone (7-beta-OH-DHEA) through a 7-keto-DHEA intermediary.
The benefits of 7-keto-DHEA supplementation are not definitively established. The current evidence is mixed and limited by factors such as small sample sizes, short study durations, and a lack of diversity in the study populations. The safety profile of 7-keto-DHEA appears to be generally well-tolerated with a low side-effect profile, but changes in blood hormone parameters have been reported. Given these uncertainties, the potential benefits and safety of 7-keto-DHEA, particularly with long-term use, are not established.
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7-keto-DHEA is not converted to hormones like androgen and estrogen
7-keto-DHEA is formed from dehydroepiandrosterone (DHEA) in the body. Unlike DHEA, 7-keto-DHEA is not converted into hormones like androgen and estrogen. Instead, it has effects that might promote weight loss by speeding up the body's metabolism and converting more energy to heat instead of storing it as fat.
DHEA is a hormone secreted by the adrenal glands, which are located just above the kidneys and are responsible for releasing stress hormones into the body. It is a precursor to the hormone androstenedione, which is then used by the body to produce both male and female sex hormones, androgen and estrogen. The amounts of DHEA in the body decrease with age and may also be depleted by certain types of drugs.
On the other hand, 7-keto-DHEA is a metabolite of DHEA that does not break down into sex hormones. By avoiding this breakdown, many of the side effects associated with DHEA are also avoided, making 7-keto-DHEA potentially safer.
Research has shown that 7-keto-DHEA may be effective for weight loss. In one study, participants who received 200 mg of 7-keto-DHEA daily for eight weeks lost an average of 6.34 pounds, while those receiving a placebo lost only 2.2 pounds. Another study found that 7-keto-DHEA increased the levels of the thyroid hormone T3, which helps regulate the body's metabolism.
It is important to note that there is currently no good scientific evidence to support the use of 7-keto-DHEA for weight loss or other conditions such as obesity, muscle strength, anxiety, and depression. While it is possibly safe when used for up to eight weeks, there is not enough information to determine its safety during pregnancy and breastfeeding, so it is recommended to avoid use during these periods.
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7-keto-DHEA is banned by WADA and may influence male hormones when used as a gel
7-keto-DHEA is a supplement that may increase your metabolism and lead to weight loss. It is formed from dehydroepiandrosterone (DHEA), a hormone produced by the adrenal glands. Unlike DHEA, 7-keto-DHEA is not converted to hormones like androgen and estrogen. Instead, it has thermogenic properties, converting more energy to heat instead of storing it as fat.
While 7-keto-DHEA does not affect hormone levels when taken orally, it may influence male sex hormones when applied to the skin as a gel. Several studies have shown that 7-keto-DHEA gel can affect male sex hormones, cholesterol, and thyroid function. However, the effects of 7-keto-DHEA gel on women are still unknown.
Due to its potential performance-enhancing effects, 7-keto-DHEA is listed as a prohibited anabolic agent by the World Anti-Doping Association (WADA). WADA's anti-doping code has been implemented by more than 660 sports organizations, including the International Olympic Committee (IOC). As such, athletes and individuals subject to performance-enhancing drug tests should avoid using 7-keto-DHEA supplements.
While 7-keto-DHEA may aid weight loss, the evidence is limited, and more research is needed to determine its effectiveness in boosting metabolism and promoting weight loss.
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Frequently asked questions
Weight loss on the keto diet varies from person to person. Generally, if you maintain a daily caloric deficit of around 500-700 calories, you can expect noticeable weight loss within 10 to 21 days.
Results may vary, but noticeable weight loss should occur after 10 to 21 days of adhering to a caloric deficit. The time it takes to meet weight loss goals differs for each individual.
According to the Cleveland Clinic, individuals on the keto diet can lose an average of 10-12 pounds in their first month if they consistently maintain a calorie deficit.
The rate of weight loss on the keto diet without exercise is around 1-2 pounds per week. Therefore, losing significant weight may take a few months.