7-Keto-DHEA is a supplement that is being promoted as a way to boost metabolism and burn fat. It is a derivative of the hormone dehydroepiandrosterone (DHEA), which is produced in the adrenal glands. Unlike DHEA, 7-Keto-DHEA does not affect sex hormone levels in the body. Some studies have shown that 7-Keto-DHEA may aid weight loss when combined with a calorie-restricted diet and exercise. However, there is limited research on the supplement, with only a few small clinical trials conducted so far. The optimal dosage is also unclear, with most studies using doses ranging from 100 to 200 mg per day. While 7-Keto-DHEA is considered safe and well-tolerated, more research is needed to fully understand its effects and potential side effects.
Characteristics | Values |
---|---|
Weight Loss | 7-Keto DHEA may promote weight loss when used alongside a diet and exercise program. |
Metabolism | 7-Keto DHEA may increase metabolism and burn fat. |
Dosage | Dosages vary from 50 mg to 200 mg per day. |
Side Effects | Side effects include hair loss, headaches, nausea, heartburn, and a metallic taste in the mouth. |
Safety | 7-Keto DHEA is likely safe and has a low risk of serious side effects when used for up to 8 weeks. |
What You'll Learn
7-Keto-DHEA dosage for weight loss
7-Keto-DHEA is a supplement that may increase your metabolism and lead to weight loss. It is a derivative of the hormone dehydroepiandrosterone (DHEA), which is produced in the adrenal glands. Unlike DHEA, 7-Keto-DHEA does not actively interact with or increase the amount of sex hormones in the blood. Instead, it is used for cell metabolism and brain functions.
The appropriate dosage of 7-Keto-DHEA depends on various factors, including age, gender, and individual health conditions. Here is a breakdown of the dosage based on the available information:
Dosage in Clinical Studies
In clinical studies investigating the effects of 7-Keto-DHEA on weight loss, the dosage ranged from 100 mg to 200 mg per day. In one study, participants received either a placebo or 100 mg of 7-Keto-DHEA twice daily for eight weeks. The 7-Keto-DHEA group lost significantly more weight and lowered their body fat percentage compared to the placebo group. Another study with a similar design and duration found that participants taking 200 mg of 7-Keto-DHEA per day lost 6.3 pounds (2.88 kg), compared to a 2.1-pound (0.97 kg) weight loss in the placebo group.
Dosage in User Reviews
User reviews of 7-Keto-DHEA provide insights into the dosage used by individuals. Some users reported taking 100 mg of 7-Keto-DHEA per day, while others took two 50 mg capsules each morning. It's important to note that the recommended dosage on most 7-Keto-DHEA supplement labels is 100 mg per serving, with a suggestion to take two servings per day with food. However, one user review mentioned that the recommended dosage is 25 mg per day, indicating potential variations in dosage instructions across different brands.
Dosage for Specific Populations
The dosage of 7-Keto-DHEA may differ for specific populations, such as older men or women with PTSD. In one study, older men applied a 7-Keto gel (25 mg single doses) to their skin daily for five days, resulting in reduced cortisol levels. Another study involving women with treatment-resistant PTSD showed that a dosage of 25-150 mg/day of 7-Keto-DHEA rapidly improved PTSD symptoms.
While 7-Keto-DHEA has shown potential in promoting weight loss, it's important to note that the long-term safety and effectiveness of this supplement have not been fully established. The available studies have been relatively small and short in duration. Therefore, it is always advisable to consult a healthcare professional before taking any supplement, especially if you have specific health concerns or are taking medication.
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7-Keto-DHEA's effectiveness for weight loss
7-Keto-DHEAs Effectiveness for Weight Loss
Overview
7-keto-DHEA is a supplement that may increase your metabolism and lead to weight loss. It is a derivative of dehydroepiandrosterone (DHEA), a hormone produced in the adrenal glands. Unlike DHEA, 7-keto-DHEA does not actively interact with sex hormones and therefore does not increase their levels in the blood when taken orally. However, it may influence sex hormones when applied to the skin as a gel.
Effectiveness for Weight Loss
The effectiveness of 7-keto-DHEA for weight loss has been explored in a limited number of studies. Here is a summary of the key findings:
- Increased metabolism: In one study, 7-Keto was found to increase the resting metabolic rate (RMR) of overweight individuals. This increase in metabolism could potentially lead to weight loss.
- Weight loss in overweight individuals: In an eight-week study, participants who received 200 mg per day of 7-Keto while following a calorie-restricted diet and exercising three days per week lost significantly more weight (6.3 pounds) compared to the placebo group (2.1 pounds).
- Combination with other supplements: In another study, researchers investigated the effects of a supplement containing 7-keto-DHEA combined with seven other ingredients thought to have an additive effect. Participants who received this supplement while adhering to a reduced-calorie diet and exercising lost significantly more weight (4.8 pounds) than those in the placebo group (1.6 pounds). However, it is unclear if this effect can be solely attributed to 7-Keto.
- Animal studies: 7-Keto has shown promising results in animal studies. In mice, it stimulated weight loss by reducing appetite, which is crucial for weight loss.
- Limited clinical evidence: Overall, there is limited clinical evidence supporting the use of 7-keto-DHEA for weight loss. The studies conducted so far have been small and short-term, and more research is needed to confirm its effectiveness.
Dosage
The typical dosage of 7-keto-DHEA supplements is 100 mg and 25 mg pills, with a recommended serving of two servings per day with food. In the studies mentioned above, dosages ranged from 100 mg to 200 mg per day. However, it is important to consult a healthcare professional before taking any supplements to determine the appropriate dosage for your specific needs.
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7-Keto-DHEA's side effects
7-Keto-DHEA is generally well-tolerated with a low risk of serious side effects. However, some users have reported feeling "jittery" after taking as little as 100 mg of 7-Keto per day. Other reported side effects include nausea, vertigo, heartburn, a metallic taste, and nausea.
One notable consideration regarding 7-Keto-DHEA is its potential influence on hormone levels when applied to the skin as a gel. Several studies have indicated that 7-Keto-DHEA gel can affect sex hormones, cholesterol, and thyroid function in men. The effects of the gel formulation on women remain unknown.
Additionally, 7-Keto-DHEA supplements have been linked to positive tests for performance-enhancing drugs. Consequently, the World Anti-Doping Association (WADA) has listed it as a prohibited anabolic agent. Individuals involved in sports and subject to performance-enhancing drug tests should refrain from using 7-Keto-DHEA supplements.
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7-Keto-DHEA's safety profile
7-Keto-DHEA has a generally well-tolerated safety profile with a low side-effect profile, but changes in blood hormone parameters have been reported. There is no good scientific evidence for its effectiveness in treating obesity, muscle strength, anxiety, depression, and many other conditions. It is possibly safe when used for up to 8 weeks and is well-tolerated in the short term. However, there is insufficient information to determine its safety for pregnant or breastfeeding women, so it is recommended to avoid it during these periods.
The US Food and Drug Administration (FDA) has not added 7-Keto-DHEA to the list of bulk drug substances due to a lack of clinical evidence regarding its safety and efficacy. The World Anti-Doping Agency (WADA) has listed it as a prohibited anabolic agent, and it may trigger positive tests for performance-enhancing drugs.
Some users have reported feeling "jittery" after taking as little as 100 mg of 7-Keto per day. A safety study showed that 7-Keto did not raise estrogen or testosterone levels or produce any other negative effects at levels up to 200 mg per day for eight weeks. Short-term animal studies also revealed no adverse effects with large amounts of 7-Keto. However, the long-term safety of 7-Keto for humans has not been established, and because it is chemically related to steroid hormones, the potential for adverse effects must be considered.
In addition, the increase in T3 (thyroid hormone) levels resulting from taking 7-Keto could theoretically produce adverse effects on the heart or promote bone loss. For these reasons, people wishing to take 7-Keto, particularly those with thyroid disorders or taking thyroid hormones, should consult a physician.
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7-Keto-DHEA's mechanism of action
7-Keto-DHEA is a non-hormonal metabolite of DHEA, which is a hormone produced by the adrenal glands. Unlike DHEA, 7-Keto-DHEA is not converted into hormones like androgen, estrogen, or testosterone. Instead, it influences the body's metabolism and energy usage, which may result in weight loss.
The mechanism of action of 7-Keto-DHEA involves increasing the body's metabolic rate and promoting the conversion of energy into heat rather than storing it as fat. This process is known as thermogenesis, and it has been observed in both human and animal studies. In one human study, participants who took 7-Keto-DHEA supplements experienced an increase in their resting metabolic rate, burning an extra 96 calories per day. Animal studies have also shown that 7-Keto-DHEA reduces alcohol consumption in rats, which may be due to its effects on the GABAA receptor complex.
Additionally, 7-Keto-DHEA has been found to have memory-enhancing effects in mice, potentially through its influence on the cholinergic system. However, more research is needed to confirm these findings. While 7-Keto-DHEA does not affect hormone levels when taken orally, it may influence sex hormones, cholesterol, and thyroid function when applied topically as a gel.
Overall, 7-Keto-DHEA appears to be well-tolerated and safe for short-term use, but more research is needed to fully understand its mechanism of action and potential long-term effects.
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Frequently asked questions
7-Keto DHEA is a supplement that may increase your metabolism and lead to weight loss. It is produced naturally in the body from dehydroepiandrosterone (DHEA), a hormone that comes from the adrenal glands. Unlike DHEA, 7-Keto DHEA does not actively interact with sex hormones.
7-Keto DHEA may promote weight loss by speeding up the body's metabolism and converting more energy to heat instead of storing it as fat. It is often used alongside a reduced-calorie diet and exercise for optimal results.
The recommended dosage of 7-Keto DHEA for weight loss is not definitive and may vary depending on individual factors. Some studies have used dosages ranging from 100 mg to 200 mg per day, taken orally or topically as a gel. It is important to consult a healthcare professional before taking any supplements.
7-Keto DHEA is generally considered safe and well-tolerated when used for up to eight weeks. However, some users have reported side effects such as hair loss, headaches, and increased heart rate. It is important to consult a healthcare professional before taking any supplements to weigh the potential benefits against the risks.