Keto And Insulin Resistance: What's The Alternative?

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The ketogenic diet is a high-fat, low-carbohydrate diet that is used for weight loss and to control symptoms of diabetes. It is believed that the diet can help with insulin resistance by lowering levels of blood glucose and insulin. However, some studies have found that the ketogenic diet may cause insulin resistance, pre-diabetes, and diabetes in the long run. This is because the diet induces an emergency response in the body, leading to chronically high levels of sugar in the blood. Additionally, the body cannot burn carbohydrates well if there is too much fat in the diet.

Characteristics Values
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Impact on insulin levels The ketogenic diet may increase or decrease insulin levels depending on the individual.
Impact on insulin resistance The ketogenic diet may increase or decrease insulin resistance depending on the individual.
Impact on weight loss The ketogenic diet may increase weight loss.
Impact on blood glucose The ketogenic diet may increase or decrease blood glucose depending on the individual.
Impact on cholesterol The ketogenic diet may increase or decrease cholesterol depending on the individual.
Impact on triglycerides The ketogenic diet may decrease triglycerides.
Impact on inflammation The ketogenic diet may decrease inflammation.
Impact on visceral fat The ketogenic diet may decrease visceral fat.
Impact on subcutaneous fat The ketogenic diet may decrease subcutaneous fat.
Impact on liver fat The ketogenic diet may decrease liver fat.
Impact on athletic performance The ketogenic diet may improve athletic performance.
Impact on satiety The ketogenic diet may increase satiety.
Impact on energy expenditure The ketogenic diet may increase energy expenditure.

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The keto diet can cause insulin resistance, pre-diabetes, or diabetes

The keto diet is a low-carb, high-fat diet that causes the body to burn fat instead of carbohydrates, resulting in weight loss. However, there is growing evidence that the keto diet can also cause insulin resistance, pre-diabetes, or diabetes. Here are some reasons why:

The keto diet induces an emergency response in the body

The keto diet is a high-fat diet that requires individuals to consume 50 grams or less of carbohydrates daily. This means that the body has to use fat as its primary energy source, which is not what humans are designed to do except in emergency situations. As a result, the body experiences chronic exposure to stress hormones 24/7, 365 days a year, leading to chronically high levels of sugar in the blood. Over time, this can lead to insulin resistance, pre-diabetes, or diabetes.

The body cannot burn carbohydrates well if there is too much fat in the diet

This concept is known as the Randle Cycle. When there is too much fat in the diet, as is the case with the keto diet, the body's ability to burn carbohydrates decreases. This means that when carbohydrates are reintroduced after a keto diet, the body doesn't know how to handle them, leading to poor carbohydrate tolerance and insulin resistance.

The keto diet may not address the root cause of poor carb tolerance

In the short term, the keto diet can improve labs and values that indicate insulin resistance by eliminating trigger foods like sugar and glucose. However, this approach does not address the root cause of poor carb tolerance. In the long run, the keto diet can actually worsen insulin resistance and increase the risk of pre-diabetes or diabetes.

Individual factors play a role in the development of insulin resistance

The degree to which improved insulin sensitivity is maintained in the long term depends on individual factors such as the duration of insulin resistance and physical activity level. Some people may find that continuing a well-formulated keto diet is most effective for maintaining metabolic health, while others may need to reintroduce carbohydrates gradually and monitor biomarkers to prevent the redevelopment of insulin resistance.

The keto diet may not be sustainable for everyone

The keto diet can be challenging to follow due to confusion around what constitutes a well-formulated ketogenic diet. It may also be difficult to meet all vitamin and mineral needs, which can contribute to poor blood sugar regulation. Additionally, the dietary restrictions required to sustain ketosis may make the keto diet unsustainable for some individuals.

In conclusion, while the keto diet may have short-term benefits, there is evidence that it can cause insulin resistance, pre-diabetes, or diabetes in the long term. It is important to carefully consider the potential risks and benefits before starting any diet, and to work with a healthcare professional to monitor your health and make any necessary adjustments.

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The body cannot burn carbohydrates well if there is too much fat in the diet

The body's ability to burn carbohydrates is hindered by the presence of excessive fat in the diet. This phenomenon is known as the Randle Cycle, which was discovered by Dr. Randle in the 1960s. Essentially, when there is an abundance of fat in the diet, as seen in a ketogenic diet or a typical American diet, the body's capacity to burn carbohydrates decreases. This is because the body's need to burn carbohydrates is significantly reduced while adhering to a ketogenic diet, which in turn impairs its ability to process carbohydrates effectively when they are reintroduced into the diet. This is similar to the concept of "if you don't use it, you lose it," where the body's capacity to perform a function diminishes when it is not regularly utilized.

The ketogenic diet is a high-fat diet that typically involves consuming 50 grams or less of carbohydrates daily. This diet induces an emergency response in the body, as humans are not designed to burn fat except in emergency situations. By following a ketogenic diet, individuals create a chronic emergency situation in their bodies, leading to elevated levels of stress hormones 24 hours a day, 7 days a week, 365 days a year. The purpose of these stress hormones is to increase the body's access to energy, which, in this case, is sugar. As a result, the body experiences chronically high levels of sugar in the blood, which can lead to long-term insulin resistance, prediabetes, or even diabetes.

The ketogenic diet not only affects the body's ability to process carbohydrates but also impacts visceral and subcutaneous fat. Visceral fat has a more significant influence on insulin sensitivity than subcutaneous fat. Reducing visceral fat can lead to improved metabolic health and insulin sensitivity. Studies have shown that ketogenic diets effectively reduce visceral adipose tissue depots, even in sedentary and athletic individuals.

Furthermore, ketogenic diets have been found to act on skeletal muscle with an "exercise-type" mechanism. When combined with exercise, ketogenic diets can enhance skeletal muscle mitochondrial capacity and efficiency, optimizing fat oxidation and improving metabolic health markers.

In conclusion, while ketogenic diets may offer potential benefits such as weight loss and increased energy levels, it is important to consider the potential long-term effects on the body's ability to burn carbohydrates effectively. The inverse relationship between fat and carbohydrate burning, as described by the Randle Cycle, highlights the importance of balancing fat and carbohydrate intake to maintain overall metabolic health.

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The keto diet induces an emergency response in the body

The ketogenic diet is a high-fat, low-carb diet. When followed strictly, it requires an individual to consume 50 grams or fewer carbohydrates daily. This diet is based on a misunderstanding of how the body is designed to burn fat. Humans are not designed to burn fat, except in emergency situations.

The keto diet creates an emergency situation in the body, leading to chronic exposure to stress hormones. The purpose of these stress hormones is to increase access to energy for the body. This energy is in the form of sugar, leading to chronically high levels of sugar in the blood. Long-term excess sugar in the blood can cause insulin resistance, pre-diabetes, or even diabetes.

The ketogenic diet and insulin resistance

The ketogenic diet can cause insulin resistance, pre-diabetes, or diabetes. This is due to the diet's high-fat content. When there is too much fat in the diet, the body's ability to burn carbohydrates decreases. This is known as the Randle Cycle.

The body's response to the keto diet

The keto diet can lead to several side effects, including:

  • Dehydration
  • Gastrointestinal issues, such as constipation, diarrhea, nausea, or vomiting
  • Kidney stones
  • Ketoacidosis
  • Reduced athletic performance
  • Vitamin and mineral deficiencies
  • Weight regain after stopping the diet

The keto diet and diabetes

Ketosis can occur in people with diabetes due to a lack of insulin or the body's inability to use insulin correctly. The keto diet may be beneficial for people with type 2 diabetes, as it focuses on reducing carbohydrate intake. However, it is important for people with diabetes to monitor their ketone levels carefully to avoid ketoacidosis, a dangerous condition caused by high levels of ketones in the blood.

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The body needs time to adjust to burning carbs again after keto

When reintroducing carbohydrates after a period of keto, the body needs time to adjust to burning carbs again. This is because the body has become more efficient at using fat as a fuel source and less efficient at using carbohydrates. This phenomenon is known as carbohydrate intolerance or carbohydrate sensitivity. It is a normal response when the body is adapting to changes in diet.

The body's metabolism is like a hybrid car that can use both gas and electric power for energy (i.e., fat and carbs). However, if you've been limiting your body to one source of energy (fat), it'll take some time to gradually become efficient at using the other one (carbs) again.

For most people, it can take about 2 weeks to readjust to carbs. This transition is slow, just like starting keto, so it's important to be patient and keep track of how you feel.

To help with the transition, start by estimating your daily carb intake on keto and increase that by 25% every week until you reach your desired amount of carbs. It's key to work your way up gradually. If you experience constipation, increased appetite, energy crashes, or other unusual symptoms, reduce your carb intake. Mild bloating or fatigue may last a little longer but will dissipate as your body adjusts.

  • Eat fiber (vegetables) and proteins/fats first, and carbs last. (This slows the absorption of glucose into your bloodstream.)
  • Drink a 10-ounce glass of water with a tablespoon of apple cider vinegar before or during your meal to reduce post-meal glucose spikes.
  • Avoid eating carbs later in the evening, when your body is less sensitive to insulin.
  • Incorporate post-meal walks into your daily routine (even just 2-15 minutes).
  • Exercise regularly (preferably both aerobic and resistance training) to improve insulin sensitivity and cardiometabolic health.
  • Get adequate sleep to live in alignment with your body clock. (One night of bad sleep can disrupt your body's ability to regulate glucose.)

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The keto diet is not a long-term solution

The keto diet is a low-carb, high-fat diet that causes the body to burn fat instead of carbohydrates. This process is known as ketosis. The keto diet is often used to help with weight loss and to control symptoms of type 2 diabetes. However, the keto diet is not a long-term solution. Here are some reasons why:

The keto diet is not sustainable

The keto diet is not a sustainable long-term solution for most people. It can be difficult to follow and maintain, especially for people with type 2 diabetes. This is partly because the keto diet is restrictive and can be confusing to implement correctly.

The keto diet can cause insulin resistance

The keto diet can lead to insulin resistance, which is a condition where cells throughout the body no longer respond to the normal actions of the hormone insulin. Insulin resistance can cause an increase in blood sugar levels and can lead to prediabetes, diabetes, and other chronic health disorders. The keto diet can also lead to chronically high levels of sugar in the blood, which can contribute to insulin resistance.

The keto diet may increase the risk of type 2 diabetes

A mouse study found that the keto diet may increase the risk of type 2 diabetes. The study showed that the keto diet doesn't allow the body to properly use insulin, leading to insulin resistance and potentially raising the risk of type 2 diabetes. However, it's important to note that more research is needed, especially in humans, to fully understand the effects of the keto diet on the body.

The keto diet may not be suitable for everyone

The keto diet may not be suitable for everyone, especially those with certain medical conditions. For example, people with chronic renal failure or type 1 diabetes should not follow the keto diet. Additionally, the keto diet can be challenging for people with type 2 diabetes to follow and maintain.

There are alternative approaches to managing insulin resistance and type 2 diabetes

There are alternative approaches to managing insulin resistance and type 2 diabetes that may be more sustainable and effective than the keto diet. These include calorie restriction, weight loss, exercise, and carbohydrate moderation. It's important to work with a healthcare professional to find an approach that is safe and effective for your individual needs.

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Frequently asked questions

Insulin resistance is a condition in which cells throughout the body no longer respond to the normal actions of the hormone insulin. More specifically, muscle, liver, and fat cells have difficulty absorbing glucose from the bloodstream. In order to compensate for this, the body produces more insulin.

An estimated 24% of US adults aged 20 years or older have the condition. Interestingly, many people with insulin resistance are unaware they have it until they develop type 2 diabetes or another serious, chronic condition. That is why it is crucial to get screened every three years if you are 45 years or older or have a risk condition that puts you at increased risk for insulin resistance. Additionally, it is important to get tested if you have one of the following conditions that put you at risk:

- Being overweight or obese

- A waist measurement over 40 in for men and 35 in for women

- Having cardiovascular disease

- Exercising minimally

- Having a familial history of diabetes

- Being of Hispanic, African-American, American Indian, Pacific Islander, or Asian American origin

- Having high blood pressure of 140/90 mmHg or above

- HDL cholesterol levels below 35 mg/dL and/or triglyceride levels above 250 mg/dL

- Having polycystic ovary syndrome (PCOS)

The best way to treat insulin resistance is to modify one’s lifestyle behaviors. Weight-loss and exercise are considered to be the most effective methods in restoring the ability of tissues to properly respond to insulin. Additionally, smoking contributes to insulin resistance, so many physicians recommend reducing or ceasing smoking altogether. In order to reduce insulin secretion, dietitians also recommend lowering carbohydrate intake.

The keto diet may substantially increase insulin sensitivity in obese subjects with type 2 diabetes. Low-carbohydrate ketogenic diets decrease fasting insulin levels compared to moderate and low fat diets in overweight subjects with elevated levels of lipids who are otherwise healthy. Low carb ketogenic diets have a greater impact on metrics related to diabetes, such as fasting insulin levels, in obese and overweight individuals when compared to standard low-fat/drug weight-loss interventions. Fasting insulin levels in the LCKD subjects decreased by over three times compared to the low-fat subjects. Ketogenic diet may help with insulin resistance in obese children. The ketogenic diet can benefit insulin resistance and recovery in athletes. Taking supplements of omega-3 fatty acids while on the ketogenic diet may confer additional benefits on metrics related to diabetes such as insulin resistance and levels of blood triglycerides and inflammatory markers in healthy, overweight subjects.

The keto diet helps us sustain a calorie deficit, which increases insulin sensitivity. The keto diet helps us lose fat, decrease our insulin response to meals, and reap the benefits of ketones.

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