7-Keto-DHEA is a supplement that may increase metabolism and lead to weight loss. It is produced from dehydroepiandrosterone (DHEA), a hormone that comes from the adrenal glands. Unlike DHEA, 7-Keto-DHEA is not converted to hormones like androgen and estrogen. It is often used for obesity, muscle strength, anxiety, and depression, but there is no scientific evidence to support these uses. A safety study in humans has shown that 7-Keto-DHEA did not raise estrogen or testosterone levels or produce any other negative effects at levels up to 200 mg per day for eight weeks. However, the long-term safety of 7-Keto-DHEA for humans has not been demonstrated, and because it is chemically related to steroid hormones, there is a potential for adverse effects.
Characteristics | Values |
---|---|
Formation | 7-keto-DHEA is formed from dehydroepiandrosterone (DHEA) in the body. |
Conversion to hormones | Unlike DHEA, 7-keto-DHEA is not converted to hormones like androgen and estrogen. |
Uses | People take 7-keto-DHEA for obesity, muscle strength, anxiety, depression, and many other conditions, but there is no good scientific evidence to support these uses. |
Oral consumption | When taken by mouth, 7-keto-DHEA is possibly safe when used for up to 8 weeks. It seems to be well tolerated when used short-term. |
Pregnancy and breastfeeding | There isn't enough reliable information to know if 7-keto-DHEA is safe to use when pregnant or breastfeeding. |
Appropriate dose | There isn't enough reliable information to know what an appropriate dose of 7-keto-DHEA is. |
Metabolism | 7-keto-DHEA has effects that might promote weight loss by speeding up the body's metabolism and converting more energy to heat instead of storing it as fat. |
Weight loss | A safety study in humans has shown that 7-KETO did not raise estrogen or testosterone levels or produce any other negative effects at levels up to 200 mg per day for eight weeks. |
Long-term safety | The long-term safety of 7-KETO for humans has not been demonstrated, and because it is chemically related to steroid hormones, the potential for adverse effects must be considered. |
T3 levels | The increase in T3 levels resulting from taking 7-KETO could, in theory, produce adverse effects on the heart or promote bone loss. |
Gel application | 7-Keto does not affect hormone levels in the body when taken as an oral supplement, but it may influence them if applied to the skin as a gel. |
What You'll Learn
- Keto-DHEA is a supplement that may increase metabolism and lead to weight loss
- Unlike DHEA, 7-keto-DHEA is not converted to hormones like androgen and estrogen
- Keto-DHEA is well-tolerated with a low risk of serious side effects
- It is banned by WADA and may influence hormones in men when applied as a gel
- Keto-DHEA is rapidly absorbed when given as a supplement and converted to its sulfate derivative
7-Keto-DHEA is a supplement that may increase metabolism and lead to weight loss
Some dieters claim that 7-Keto-DHEA helps promote weight loss when used alongside a diet and exercise program. In one double-blind trial, participants who took 100 mg of 7-Keto-DHEA twice daily for eight weeks lost more weight and lowered their body fat percentage compared to those taking a placebo. Another eight-week study found that those taking 200 mg of 7-Keto-DHEA per day lost 6.3 pounds, compared to 2.1 pounds in the placebo group.
However, it is important to note that there is limited research on the effectiveness of 7-Keto-DHEA for weight loss. Only two studies have looked at its effects on metabolism, and the results are inconclusive. While one study found that 7-Keto-DHEA increased the resting metabolic rate, another found no difference in basal metabolic rate between those taking the supplement and those taking a placebo. More research is needed to determine the potential benefits of 7-Keto-DHEA for weight loss.
In terms of safety, 7-Keto-DHEA is likely safe and has a low risk of serious side effects when taken orally for up to eight weeks. However, it is important to consult a physician before taking this supplement, especially for those with a thyroid disorder or taking thyroid medication. Additionally, 7-Keto-DHEA can affect hormone levels when used as a gel, so it should not be used by those involved in sports as it may trigger positive tests for performance-enhancing drugs.
Coconut Milk Coffee: A Keto-Friendly Morning Brew
You may want to see also
Unlike DHEA, 7-keto-DHEA is not converted to hormones like androgen and estrogen
7-keto-DHEA is a naturally occurring metabolite of the hormone dehydroepiandrosterone (DHEA). While DHEA is a precursor to other hormones, including testosterone and estrogen, 7-keto-DHEA is not converted into these hormones. This is a key distinction between the two compounds.
DHEA is a hormone produced by the adrenal glands and is the most abundant circulating steroid in humans. It serves as a building block in the production of estrogen, testosterone, and progesterone. DHEA levels naturally decline with age, and some people use DHEA supplements to counteract this decline. However, DHEA can cause side effects such as acne, hair loss, and hormonal imbalances, especially when taken in high doses. It may also interfere with a wide range of prescription medications and herbal supplements.
On the other hand, 7-keto-DHEA is formed when DHEA is broken down by the body. It stimulates the production of enzymes that enhance thermogenesis, the process of heat production in the body. This increased thermogenesis can lead to improved metabolism and fat burning. 7-keto-DHEA has been shown to boost metabolism, aid in weight loss, and improve body composition. It may also offer cognitive-enhancing effects and bolster immune function. However, there is limited research on the effectiveness and side effects of 7-keto-DHEA, and it is not recommended for use during pregnancy or breastfeeding due to a lack of sufficient safety information.
While both 7-keto-DHEA and DHEA have potential benefits, they also come with possible side effects and risks. 7-keto-DHEA may cause insomnia, anxiety, and digestive issues in some individuals. It is important to note that natural products are not always safe, and dosages can be important. Consulting a healthcare professional before taking any supplement is crucial, especially if you have any pre-existing health conditions or are taking medications.
Ketamine: How Long Does It Stay in Your System?
You may want to see also
7-Keto-DHEA is well-tolerated with a low risk of serious side effects
7-Keto-DHEA is a supplement that may increase metabolism and lead to weight loss. It is a naturally occurring metabolite of the hormone dehydroepiandrosterone (DHEA). Unlike DHEA, 7-Keto-DHEA is not converted to hormones like androgen and estrogen. Instead, it is rapidly absorbed when given as a supplement and converted to its sulfate derivative.
There is a general consensus that 7-Keto-DHEA is well-tolerated and has a low risk of serious side effects. One study showed that the supplement was well-tolerated in men at doses up to 200 mg per day for four weeks. Another study found that 7-Keto-DHEA was well-tolerated when taken orally for up to eight weeks. However, it is important to note that the long-term safety of 7-Keto-DHEA has not been established, and there is a potential for adverse effects due to its chemical similarity to steroid hormones.
Some users have reported feeling "jittery" after taking as little as 100 mg of 7-Keto-DHEA per day. Other reported side effects in both men and women include heartburn, a metallic taste, and nausea. Additionally, 7-Keto-DHEA applied to the skin as a gel may influence hormone levels in men.
While generally considered safe, 7-Keto-DHEA supplements have been banned by the World Anti-Doping Association (WADA) due to concerns about their potential performance-enhancing effects.
Keto Dry Mouth: How Long Does It Last?
You may want to see also
It is banned by WADA and may influence hormones in men when applied as a gel
7-keto-DHEA is a supplement that may increase metabolism and lead to weight loss. It is produced naturally in the body from dehydroepiandrosterone (DHEA), a hormone that comes from the adrenal glands. DHEA is a building block in the production of estrogen, testosterone, and progesterone. Unlike DHEA, 7-keto-DHEA does not actively interact with sex hormones and is not converted into hormones like androgen and estrogen.
When taken orally, 7-keto-DHEA does not increase the amount of sex hormones in the blood. However, when applied to the skin as a gel, it may influence hormone levels in men. Several studies have shown that 7-keto-DHEA gel can affect sex hormones, cholesterol, and thyroid function in men. The World Anti-Doping Association (WADA) has listed 7-keto-DHEA supplements as a prohibited anabolic agent. This means that if you are involved in sports and are subject to performance-enhancing drug tests, you should avoid taking 7-keto-DHEA supplements.
The safety profile of 7-keto-DHEA is generally low, and it is well-tolerated with a low risk of side effects. However, it is important to consult a physician familiar with its use, especially if you are considering using it as a gel. While 7-keto-DHEA did not raise estrogen or testosterone levels in oral studies, the long-term safety of this supplement has not been established, and the potential for adverse effects must be considered due to its chemical relation to steroid hormones.
Keto Diet: Brain Fog Buster or Myth?
You may want to see also
7-Keto-DHEA is rapidly absorbed when given as a supplement and converted to its sulfate derivative
7-Keto-DHEA, also known as 7-oxo-DHEA, is a steroid produced by the metabolism of DHEA. It is not converted to testosterone or estrogen. Instead, it is rapidly absorbed when taken as a supplement and is converted to its sulfate derivative. This means that it can be used to produce the metabolic effects of DHEA while avoiding conversion to estrogen or androgen.
The benefits of 7-Keto-DHEA are supported by clinical research, which has found that it can improve metabolism and aid weight management. It may also have some anti-cortisol activity through enzyme competition, which could be beneficial for those with hypercortisolism and metabolic syndrome.
Most studies on 7-Keto-DHEA have focused on its ability to improve the metabolic rate, and results suggest that it can enhance metabolism even when an individual is on a low-calorie diet. There is also limited information indicating that 7-Keto-DHEA may increase levels of T3 in patients on a calorie-restricted diet.
In summary, 7-Keto-DHEA is a supplement that can be safely taken in the short term and may offer benefits for weight loss and metabolism by increasing the metabolic rate and potentially reducing the negative effects of cortisol. However, more research is needed to confirm these effects and evaluate the long-term safety of 7-Keto-DHEA.
When to Check Ketone Levels on Keto
You may want to see also
Frequently asked questions
7-keto DHEA is likely safe and has a low risk of serious side effects when taken orally for up to eight weeks. However, there is limited information about its long-term safety in humans.
Some people have reported feeling "jittery" after taking 7-keto DHEA. Other reported side effects include heartburn, metallic taste, and nausea.
7-keto DHEA does not increase testosterone or estrogen levels when taken orally. However, it may influence hormone levels when applied to the skin as a gel.